2-(azetidin-3-yl)-5-cyclopropylpyrimidine, bis(trifluoroacetic acid) CAS 2060059-87-0
| CAS No. | 2060059-87-0 |
| Molecular Formula | C10H13N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(azetidin-3-yl)-5-cyclopropylpyrimidine, bis(trifluoroacetic acid).
2-(azetidin-3-yl)-5-cyclopropylpyrimidine, bis(trifluoroacetic acid) (CAS 2060059-87-0), molecular formula C10H13N3C2HF3O2 and molecular weight 289.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(azetidin-3-yl)-5-cyclopropylpyrimidine, bis(trifluoroacetic acid) (C10H13N3C2HF3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(azetidin-3-yl)-5-cyclopropylpyrimidine, bis(trifluoroacetic acid) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13N3 2*C2HF3O2 |
| Molecular Weight | 289.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related azetidin Standards
- 4-(Azetidin-1-yl)cyclohexan-1-amine dihydrochloride (CAS 1001347-27-8)
- 4-(Azetidin-1-ylmethyl)-1H-indole (CAS 1001395-40-9)
- 2-(Azetidin-1-yl)acetic acid (CAS 1008304-81-1)
- Azetidin-3-yl methylcarbamate hydrochloride (CAS 1009368-29-9)
- 5-(Azetidin-3-yl)-2-methyl-tetrazole (CAS 1009409-58-8)
- 2-((Azetidin-3-yloxy)methyl)-5-methyl-1,3,4-oxadiazole (CAS 1009409-61-3)
- Azetidin-3-yl methylcarbamate (CAS 1009409-62-4)
- 1-(Azetidin-3-ylmethyl)piperidine (CAS 1012784-24-5)
Recommended Standards
- 4-Bromo-5-chloro-2-methylbenzo[d]thiazole (CAS 1427384-48-2)
- 4-(4-(Tert-butyl)benzoyl)-N-(3-(trifluoromethyl)benzyl)-1H-pyrrole-2-carboxamide (CAS 439111-61-2)
- 3,3-Difluoro-2,3-dihydrobenzofuran-7-carbaldehyde (CAS 2846109-51-9)
- Ethyl (5-phenyl-1H-benzo[d]imidazol-2-yl)carbamate (CAS 83821-08-3)
- 2-{[5-(3-chlorophenyl)-1,3-oxazol-2-yl]methoxy}aniline (CAS 1183067-04-0)
- Ethyl 1-(4-methyl-6-(trifluoromethyl)pyrimidin-2-yl)piperidine-3-carboxylate (CAS 931998-13-9)
- (2-(Tert-butyl)cyclopropyl)boronic acid (CAS 680600-46-8)
- 1-(Diphenylmethyl)-2,2-dimethylazetidin-3-amine (CAS 133891-73-3)
- 6-Bromo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine (CAS 1783932-03-5)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
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