Ethyl 1-(Chlorocarbonyl)piperidine-4-carboxylate CAS 206182-52-7
| CAS No. | 206182-52-7 |
| Molecular Formula | C9H14ClNO3 |
| Molecular Weight | 219.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 219.67 g/mol gives Ethyl 1-(Chlorocarbonyl)piperidine-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 1-(Chlorocarbonyl)piperidine-4-carboxylate (CAS 206182-52-7), molecular formula C9H14ClNO3 and molecular weight 219.67 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 1-(Chlorocarbonyl)piperidine-4-carboxylate (C9H14ClNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H14ClNO3 |
| Molecular Weight | 219.67 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2015 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 4-Methyl-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl trifluoromethanesulfonate (CAS 1373028-22-8)
- 1,2,3,7,8-Pentachlorodibenzo-p-dioxin (CAS 40321-76-4)
- Dabigatran Impurity 59 (CAS CATO-C4X-108959)
- 2-((2-(2-Methoxyphenoxy)ethyl)amino)-5-nitrobenzonitrile (CAS 852385-27-4)
- N-({2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-methylhydrazino}carbothioyl)benzenecarboxamide (CAS 338794-95-9)
- 3-Amino-2,2-dimethyl-1-(4-methylpiperazin-1-yl)propan-1-one (CAS 1248154-49-5)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
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