8-Bromo-7-methyl-6-nitroimidazo[1,2-a]pyridine CAS 2079884-46-9
| CAS No. | 2079884-46-9 |
| Molecular Formula | C8H6BrN3O2 |
| Molecular Weight | 256.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 8-Bromo-7-methyl-6-nitroimidazo[1,2-a]pyridine (CAS 2079884-46-9), a certified reference material (molecular formula C8H6BrN3O2, MW 256.06 g/mol) for analytical method development and quality control.
The molecular framework of 8-Bromo-7-methyl-6-nitroimidazo[1,2-a]pyridine (C8H6BrN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6BrN3O2 |
| Molecular Weight | 256.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 3-Bromo-6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-20-4)
- 6-Bromo-3-methyl-4-nitro-1H-indazole (CAS 1000342-18-6)
- 3-Bromo-6-methyl-5-nitro-1H-indazole (CAS 1000343-58-7)
- 5-Bromo-6-methyl-3-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 1000343-84-9)
- 8-Bromo-6-methyl-3-nitroimidazo[1,2-a]pyridine (CAS 1072944-59-2)
- 6-Bromo-7-methyl-3-nitroimidazo[1,2-a]pyridine (CAS 1072944-64-9)
- 3-Bromo-4-methyl-5-nitro (1H)Indazole (CAS 1082040-52-5)
- 3-Bromo-5-methyl-6-nitro-1H-indazole (CAS 1082040-69-4)
Recommended Standards
- 7-Bromo-1-methyl-5-nitro-1H-indazole (CAS 952183-39-0)
- Boronic acid, b-[3-[[(3-pyridinylmethyl)amino]carbonyl]phenyl]- (CAS 874288-17-2)
- 6-Bromo-2-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione (CAS 2833669-73-9)
- Boronic acid, b-[3-[[(4-pyridinylmethyl)amino]carbonyl]phenyl]- (CAS 874288-18-3)
- 1-(p-tolyl)cyclohexanecarboxylic acid (CAS 84682-27-9)
- (5-(Thiophen-2-yl)oxazol-4-yl)methanamine (CAS 1531780-67-2)
- 3-Bromo-1,2-dihydroacenaphthylene (CAS 5209-31-4)
- 5-Hydroxy-4,4-dimethyl-3-oxopentanenitrile (CAS 489432-33-9)
- 2-((3-Cyano-4,6-dimethylpyridin-2-yl)thio)-N-(3-nitrophenyl)acetamide (CAS 329934-67-0)
- (1S,2S)-2-azidocyclohexanol (CAS 119479-49-1)
- 2-(Hydroxymethyl)-3-Nitro-Phenol (CAS 57356-31-7)
- Allopurinol Impurity 32 (CAS 52632-17-4)
- Ethyl 8-hydroxy-1,4-dioxaspiro[4.5]Dec-7-ene-7-carboxylate (CAS 121210-56-8)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
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