5-Chloro-3-fluoropyridine-2-carboxylic Acid CAS 207994-08-9
| CAS No. | 207994-08-9 |
| Molecular Formula | C6H3ClFNO2 |
| Molecular Weight | 175.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 175.54 g/mol gives 5-Chloro-3-fluoropyridine-2-carboxylic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-3-fluoropyridine-2-carboxylic Acid (CAS 207994-08-9) is a high-purity analytical reference standard with the molecular formula C6H3ClFNO2 and a molecular weight of 175.54 g/mol.
The molecular framework of 5-Chloro-3-fluoropyridine-2-carboxylic Acid (C6H3ClFNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-3-fluoropyridine-2-carboxylic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3ClFNO2 |
| Molecular Weight | 175.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-5-fluoropicolinic acid (CAS 1060802-35-8)
- 6-Chloro-4-fluoropicolinic acid (CAS 1060809-28-0)
- 6-chloro-4-fluoronicotinic acid (CAS 1060809-30-4)
- 3-Chloro-5-(trifluoromethyl)-1H-1,2,4-triazole (CAS 1199215-88-7)
- 3-Chloro-6-fluoropicolinic acid (CAS 1199243-95-2)
- 2-Chloro-6-fluoroisonicotinic Acid (CAS 1211521-09-3)
- 4-Chloro-6-fluoronicotinic acid (CAS 1211525-00-6)
- 5-Chloro-2-fluoroisonicotinic acid (CAS 1211532-40-9)
Recommended Standards
- 5-Chloro-2-fluoronitrobenzene (CAS 345-18-6)
- 5-chloro-6-fluoropyridine-2-carboxylic acid (CAS 851386-30-6)
- 5-Chloro-2-fluoronicotinic Acid (CAS 884494-57-9)
- 6-Chloro-5-fluoronicotinic acid (CAS 38186-86-6)
- (2R)-1-(tert-Butyldimethylsilyl)-4-oxoazetidine-2-carboxylic acid (CAS 162856-35-1)
- 2-Amino-5-(ethylsulfonyl)-4-(4-methoxyphenyl)thiophene-3-carbonitrile (CAS 1713714-29-4)
- 3-(Naphthalen-2-yl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one (CAS 24282-95-9)
- (2S,4R)-4-Ethyl-1-methylproline Hydrochloride (CAS 2880-73-1)
- 866145-26-8 (1-Ethyl-1H-indol-3-yl)(piperidino)methanone MFCD04126328 (CAS 866145-26-8)
- 1-(4-(5-(4-Chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyrazol-3-yl)piperidin-1-yl)-2-hydroxyethan-1-one (CAS 271576-80-8)
- Monosialoganglioside G<SUB>M2</SUB> derived from bovine brain (CAS 19600-01-2)
- Dydrogesterone Impurity 14 (CAS 7488-73-5)
- 1-Tosylindolin-6-amine (CAS 927997-18-0)
- 107444-51-9 0JS9125PIZ Glucagon-like peptide 1 (7-36) Glucagon-related peptide 1 (Rana catesbeiana), 3-L-glutamic acid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-30-L-argininamide-31-de-L-proline-32-de-L-lysine- Glp-I (7-36) Proglucagon (78-107) Human glucagon-like peptide-1-(7-36) amide Human GLP-1-(7-36)-amide Glucagon-like peptide-I(7-36) amide Rat GLP-I(7-36)amide Insulinotropin (human) MKC 253 UNII-0JS9125PIZ (CAS 107444-51-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com