Ethyl 3-chloro-5-pyridinecarboxylate CAS 20825-98-3
| CAS No. | 20825-98-3 |
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ethyl 3-chloro-5-pyridinecarboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ethyl 3-chloro-5-pyridinecarboxylate (CAS 20825-98-3) is a high-purity analytical reference standard with the molecular formula C8H8ClNO2 and a molecular weight of 185.61 g/mol.
The molecular framework of Ethyl 3-chloro-5-pyridinecarboxylate (C8H8ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 2-(6-Chloro-5-methylpyridin-3-yl)acetic acid (CAS 1000546-06-4)
- 2-(2-chloro-6-methylpyridin-3-yl)acetic acid (CAS 1000567-19-0)
- 2-(6-chloro-2-methylpyridin-3-yl)acetic acid (CAS 1000568-04-6)
- 2-Chloro-N-(2-hydroxyphenyl)acetamide (CAS 10147-68-9)
- 2-Chloro-n-(3-hydroxyphenyl)acetamide (CAS 10147-69-0)
- 3-Chloro-5,6-dimethylpyridazine-4-carboxamide (CAS 1019117-07-7)
- 3-Chloro-4-hydroxy-N-methylbenzamide (CAS 1019353-18-4)
- 4-Chloro-2-hydroxy-N-methylbenzamide (CAS 105417-10-5)
Recommended Standards
- Ethyl 2-Chloropyridine-4-carboxylate (CAS 54453-93-9)
- Ethyl 3-chloroisonicotinate (CAS 211678-96-5)
- D-(+)-(2-Chlorophenyl)glycine (CAS 86169-24-6)
- Ethyl 4-chloronicotinate, 97% (CAS 37831-62-2)
- 4-(4-Ethoxyphenyl)-5-methyloxazol-2(3H)-one (CAS 313684-12-7)
- Amphetaminil (Mixture of Diastereomers) (1.0mg/ml in Acetonitrile) (CAS 17590-01-1)
- 3-(1H-Imidazol-1-yl)-N-methylpropan-1-amine dihydrochloride (CAS 1357353-01-5)
- N-Methyl-6-nitro-1,2-benzoxazole-3-carboxamide (CAS 400079-08-5)
- 2-Butylbenzo[d]oxazole-5-carboxylic acid (CAS 885949-50-8)
- Isothiazole-5-methanamine Hydrochloride (CAS 2095410-14-1)
- 2-chloro-3-(iodomethyl)-6-methyl-pyridine (CAS 2755893-20-8)
- 5-Methoxypyrazine-2-sulfonyl chloride (CAS 1108654-58-5)
- N-Methylacetamide-d7 (CAS 3669-74-7)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
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