4-Hydroxybenzyl isothiocyanate CAS 2086-86-4
| CAS No. | 2086-86-4 |
| Molecular Formula | C8H7NOS |
| Molecular Weight | 165.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Hydroxybenzyl isothiocyanate (CAS 2086-86-4), a certified reference material (molecular formula C8H7NOS, MW 165.21 g/mol) for analytical method development and quality control.
The molecular framework of 4-Hydroxybenzyl isothiocyanate (C8H7NOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-Hydroxybenzyl isothiocyanate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7NOS |
| Molecular Weight | 165.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Hydroxybenzyl Standards
- N-(2-Hydroxybenzyl)acetamide (CAS 80311-94-0)
- N-(4-Hydroxybenzyl)acetamide (CAS 34185-04-1)
- 4-Hydroxybenzyl acetate (CAS 80767-12-0)
- 1-(4-Hydroxybenzyl)cyclopropane-1-carbonitrile (CAS 1871914-87-2)
- N-(4-hydroxybenzyl)-N-methylacetamide (CAS 886493-61-4)
- 1-((4-Hydroxybenzyl)oxy)propan-2-one (CAS 952101-44-9)
- (2-Hydroxybenzyl)glycine (CAS 2233-84-3)
- (4-Hydroxybenzyl)glycine (CAS 22094-71-9)
Recommended Standards
- 4-(Methylsulfinyl)benzonitrile (CAS 97474-48-1)
- 4-Methoxy-1,2-benzisothiazole (CAS 35272-30-1)
- 4-(2-Furyl)-2-methylthiazole (CAS 492440-71-8)
- 4-Methoxy-1,2-thiazinane 1,1-dioxide (CAS 291514-18-6)
- 1-(butan-2-yl)-1H-imidazole (CAS 20075-29-0)
- Methyl (E)-3-(5-((((2,6-dichlorobenzyl)oxy)imino)methyl)furan-2-yl)thiophene-2-carboxylate (CAS 241488-16-4)
- 2,5-Dioxopyrrolidin-1-yl 4-(3-tosyl-2-(tosylmethyl)propanoyl)benzoate (CAS 899452-51-8)
- 2-Methyl-1-phenyl-2-propanol (CAS 100-86-7)
- 3-(5-methyl-1,2,4-oxadiazol-3-yl)-8-azabicyclo[3.2.1]octane hydrochloride (CAS 2060005-01-6)
- 2-Methyl-1-(methylamino)-[1,2,4]triazolo[1,5-b]isoquinolin-5(1H)-one (CAS 60437-70-9)
- 2-Amino-5-cyanopyridine-3-carboxamide (CAS 89795-83-5)
- 7-bromoisoquinoline-1-carbonitrile (CAS 1204334-25-7)
- 5-((4-Methoxyphenyl)thio)pentan-2-one (CAS 1153195-29-9)
- Semaglutide impurity 95 (CAS CATO-C4X-222695)
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