(Z)-4-((5-Chloro-2-methylphenyl)amino)-4-oxobut-2-enoic acid CAS 208663-08-5
| CAS No. | 208663-08-5 |
| Molecular Formula | C11H10ClNO3 |
| Molecular Weight | 239.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (Z)-4-((5-Chloro-2-methylphenyl)amino)-4-oxobut-2-enoic acid.
(Z)-4-((5-Chloro-2-methylphenyl)amino)-4-oxobut-2-enoic acid (CAS 208663-08-5) is a high-purity analytical reference standard with the molecular formula C11H10ClNO3 and a molecular weight of 239.66 g/mol.
(Z)-4-((5-Chloro-2-methylphenyl)amino)-4-oxobut-2-enoic acid (C11H10ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (Z)-4-((5-Chloro-2-methylphenyl)amino)-4-oxobut-2-enoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10ClNO3 |
| Molecular Weight | 239.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Z Standards
- Ethyl 7-chloro-2-methyl-2H-pyrazolo[4,3-b]pyridine-6-carboxylate (CAS 100478-09-9)
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- 4-[(2-Chloro-3-pyridinyl)carbonyl]-2-piperazinone (CAS 1016743-92-2)
- 4-((3-Chloro-4-methylphenyl)amino)-4-oxobut-2-enoic acid (CAS 116081-44-8)
- 2-Chloro-N-(4,6-dimethyl-isoxazolo[5,4-b]pyridin-3-yl)-acetamide (CAS 1171935-26-4)
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Recommended Standards
- (S)-2-(2-Oxo-4-phenyloxazolidin-3-yl)acetyl chloride (CAS 99333-55-8)
- 1-(2-Chloroacetyl)-4,6-dimethyl-1,2-dihydro-3h-pyrazolo[3,4-b]pyridin-3-one (CAS 853574-46-6)
- (E)-4-[(2-Chlorobenzyl)amino]-4-oxo-2-butenoic acid (CAS 904785-36-0)
- 1-(2-Chlorophenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 91349-19-8)
- 2-Pyridinecarbonitrile, 5-fluoro-1,6-dihydro-6-oxo- (CAS 1239510-82-7)
- 2,5-dimethyl-1-(5-methylisoxazol-3-yl)-1H-pyrrole-3-carbaldehyde (CAS 851398-35-1)
- 1-Isopropyl-4-(4-isopropylphenyl)-6-methoxy-3,4-dihydroquinazolin-2(1H)-one (CAS 37749-76-1)
- 5-(Chloromethyl)-N-(2,6-dimethylphenyl)isoxazole-3-carboxamide (CAS 139297-40-8)
- 2,3-Diphenyl-5-ethyltetrazolium Chloride (CAS 66138-05-4)
- Ethyl 1H-pyrrolo[3,2-c]pyridine-4-carboxylate (CAS 1167056-36-1)
- 2-Bromo-4,5-dihydro-6h-pyrrolo[3,4-d]thiazol-6-one (CAS 1211531-11-1)
- (1-(1-(Pyrazin-2-yl)ethyl)piperidin-2-yl)methanol (CAS 1289387-14-9)
- L-Alanine-2-d1-N-FMOC (CAS 225101-64-4)
- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
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