Onametostat (JNJ-64619178) CAS 2086772-26-9
| CAS No. | 2086772-26-9 |
| Molecular Formula | C22H23BrN6O2 |
| Molecular Weight | 483.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Onametostat (JNJ-64619178) (CAS 2086772-26-9), molecular formula C22H23BrN6O2 and molecular weight 483.36 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Onametostat (JNJ-64619178) (C22H23BrN6O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H23BrN6O2 |
| Molecular Weight | 483.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 6 |
Recommended Standards
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- 9-(Chloroacetyl)-2,3,4,9-tetrahydro-1h-carbazole (CAS 43170-54-3)
- PACAP-Related Peptide (PRP), rat (CAS 132769-35-8)
Why CATO?
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