Trelagliptin Impurity 6 CAS 2087874-94-8
| CAS No. | 2087874-94-8 |
| Molecular Formula | C40H42F2N10O6 |
| Molecular Weight | 796.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Trelagliptin Impurity 6.
As a process- or degradation-related impurity, Trelagliptin Impurity 6 (CAS 2087874-94-8, C40H42F2N10O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Trelagliptin Impurity 6 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 796.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Trelagliptin Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C40H42F2N10O6 |
| Molecular Weight | 796.82 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 10 |
Related Trelagliptin Standards
- Trelagliptin Impurity 77 (CAS CATO-C4X-104677)
- Trelagliptin Impurity 24 (CAS CATO-C4X-104624)
- Trelagliptin Impurity 52 (CAS CATO-C4X-104652)
- Trelagliptin impurity 71 (CAS 2204313-60-8)
- Trelagliptin impurity 80 (CAS CATO-C4X-104680)
- Trelagliptin impurity 86 (CAS CATO-C4X-104686)
- Trelagliptin Impurity 10 (CAS CATO-C4X-104610)
- Trelagliptin Impurity 34 (CAS 1917324-13-0)
Recommended Standards
- 4,4',4",4"'-(9,9'-Spirobi[fluorene]-2,2',7,7'-tetrayl)tetrabenzoic acid (CAS 1350363-07-3)
- (5R,9R)-5,9-Bis(2-(cyclohexyloxy)naphthalen-1-yl)-7-hydroxydinaphtho[2,3-d:2',3'-f][1,3,2]dioxaphosphepine 7-oxide (CAS 1016637-36-7)
- O-Methyl-O-(N-Butylfluorescein)-O-{3-[6-O-(D,L-1-ethoxyethyl)-1,2:4,5-bis-O-(1-methylethylidene)-D,L-myo-inositol]}phosphate (CAS 335630-21-2)
- Dinaphtho[2,3-d:2′,3′-f][1,3,2]dioxaphosphepin, 5,9-bis[2-(cyclohexyloxy)-1-naphthalenyl]-7-hydroxy-, 7-oxide (CAS 2168567-88-0)
- Riluzole Impurity 23 (CAS CATO-C4X-200923)
- Sildenafil Impurity 28 (CAS 139756-26-6)
- Rosuvastatin Impurity 81 (CAS 854898-47-8)
- 5-Azaspiro[2.4]Heptane-7-carbonitrile (CAS 2091055-02-4)
- 2-Bromomethyl-3-fluoro-6-(trifluoromethyl)pyridine (CAS 1227573-58-1)
- 2-((5-(Benzo[d][1,3]dioxol-5-yl)-1,3,4-oxadiazol-2-yl)thio)-N-(cyclohexylmethyl)acetamide (CAS 854025-80-2)
- 7-Chloro-2H-benzo[b][1,4]oxazine (CAS 1209893-43-5)
- tert-Butyl 4-(6-acetamido-5-methylpyridin-3-yl)piperidine-1-carboxylate (CAS 1820614-58-1)
- Apremilast Impurity 73 (CAS CATO-C4X-100973)
- Semaglutide impurity 210 (CAS CATO-C4X-2226210)
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