4-Fluoro-2-((6-methoxy-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile (Trelagliptin Impurity) CAS 2088203-83-0
| CAS No. | 2088203-83-0 |
| Molecular Formula | C14H12FN3O3 |
| Molecular Weight | 289.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Fluoro-2-((6-methoxy-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile (Trelagliptin Impurity).
4-Fluoro-2-((6-methoxy-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile (Trelagliptin Impurity) (CAS 2088203-83-0) is a high-purity analytical reference standard with the molecular formula C14H12FN3O3 and a molecular weight of 289.26 g/mol.
4-Fluoro-2-((6-methoxy-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile (Trelagliptin Impurity) (C14H12FN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Fluoro-2-((6-methoxy-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile (Trelagliptin Impurity) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12FN3O3 |
| Molecular Weight | 289.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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- Methyl 5-[3-fluoro-4-(methoxycarbonyl)phenyl]pyridine-3-carboxylate (CAS 1820666-85-0)
- Methyl 3-(3-fluoro-2-methylphenyl)-5-nitrobenzoate (CAS 1820740-67-7)
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Recommended Standards
- 4-(3-(4-(Trifluoromethyl)phenyl)-1H-pyrazol-4-yl)pyridine (CAS 396129-66-1)
- 4-(2-Fluorobenzoyl)-N-[(methoxyimino)methyl]-1H-pyrrole-2-carboxamide (CAS 338977-17-6)
- 4-Fluoro-N-(2-(2-(furan-2-ylmethylene)hydrazinyl)-2-oxoethyl)benzamide (CAS 330964-61-9)
- 3-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazole (CAS 89804-59-1)
- 1-(2,3-Dimethylphenyl)-4-(1-(2-methoxyethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one (CAS 915188-66-8)
- (3,5-Dichloropyridin-4-yl)(phenyl)methanol (CAS 402561-69-7)
- Methyl 3-amino-3-(3,5-difluorophenyl)propanoate (CAS 1425354-22-8)
- Isobutyl 1-(furan-2-ylmethyl)piperidine-4-carboxylate (CAS 1031843-74-9)
- 1-(2-Chlorophenyl)-2-Thiourea (CAS 5344-82-1)
- 1-methoxy-2-(3-methylbut-2-en-1-yl)benzene (CAS 4957-17-9)
- 6-Bromo-3-(bromomethyl)-5-(difluoromethyl)picolinaldehyde (CAS 1804489-19-7)
- 3-(Pyrimidin-5-yl)-1H-pyrazol-5-amine (CAS 1988685-94-4)
- 2-((4-Nitrophenoxy)methyl)-1,3-dioxolane (CAS 179246-35-6)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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