Thiophen-2(3H)-one CAS 20893-64-5
| CAS No. | 20893-64-5 |
| Molecular Formula | C4H4OS |
| Molecular Weight | 100.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Thiophen-2(3H)-one is closely related to sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Thiophen-2(3H)-one (CAS 20893-64-5), molecular formula C4H4OS and molecular weight 100.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Thiophen-2(3H)-one (C4H4OS) is characterized by sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H4OS |
| Molecular Weight | 100.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Sulfur Atoms | 1 |
Related Thiophen Standards
- Thiophen-3-ol (CAS 17236-59-8)
- Thiophen-3(2H)-one 19090-02-9 (CAS 19090-02-9)
- Thiophen-5-d-2-amine (CAS 1185309-42-5)
- Thiophen-2(3H)-imine (CAS 82357-68-4)
- (thiophen-3-yl)acetylene 3-ethynyl thiophene; 67237-53-0 EBD14411 (CAS 67237-53-0)
- Thiophen-2-ylmethanamine hydrochloride (CAS 7404-63-9)
- Thiophen-2-ylhydrazine (CAS 90927-92-7)
- 2-(Thiophen-3-yl)acetaldehyde (CAS 114633-95-3)
Recommended Standards
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- 3354-32-3 2(5H)-Thiophenone DTXSID50187193 (CAS 3354-32-3)
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- CAS 70211-36-8 (CAS 70211-36-8)
- Methyl 6-methoxy-2h-chromene-8-carboxylate (CAS 1221724-24-8)
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- 6,7-Dimethoxy-1,2,3,4-tetrahydroquinoline (CAS 99986-04-6)
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- 4-Amino-3,3-dimethylpyrrolidin-2-one (CAS 1505180-72-2)
- 2,2,2-Trifluoro-1-(2-(isopentylthio)phenyl)ethan-1-one (CAS 1443327-10-3)
- 3-O-Methyl 6-Hydroxy-17β-estradiol 17-O-Tetrahydropyran (CAS 473882-84-7)
- Tirzepatide Impurity 33 (CAS CATO-C4X-324033)
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