tert-Butyl (R)-(4,4-difluoropiperidin-3-yl)carbamate CAS 2089321-22-0
| CAS No. | 2089321-22-0 |
| Molecular Formula | C10H18F2N2O2 |
| Molecular Weight | 236.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), tert-Butyl (R)-(4,4-difluoropiperidin-3-yl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
tert-Butyl (R)-(4,4-difluoropiperidin-3-yl)carbamate (CAS 2089321-22-0), molecular formula C10H18F2N2O2 and molecular weight 236.26 g/mol, is a CATO reference standard with documented purity and traceability.
tert-Butyl (R)-(4,4-difluoropiperidin-3-yl)carbamate (C10H18F2N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H18F2N2O2 |
| Molecular Weight | 236.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl (5S)-5-amino-3,3-difluoropiperidine-1-carboxylate (CAS 2055848-76-3)
- tert-Butyl (R)-(5,5-difluoropiperidin-3-yl)carbamate (CAS 2089320-98-7)
- Tert-butyl (4-amino-2,2-difluorocyclopentyl)carbamate (CAS 2168368-63-4)
- Tert-butyl (R)-2-(difluoromethyl)piperazine-1-carboxylate (CAS 2165480-74-8)
- 2-Amino-N-(thiophen-3-ylmethyl)acetamide (CAS 1340319-01-8)
- (S)-4-(1-Aminoethyl)-3-(trifluoromethyl)benzonitrile (CAS 1388123-31-6)
- 1-[(2S)-2-(pyridin-3-yl)pyrrolidin-1-yl]ethan-1-one (CAS 5979-94-2)
- 1-(6-Methoxybenzo[d]oxazol-2-yl)ethanamine (CAS 1600439-36-8)
- Methyl 7-oxa-2-azabicyclo[4.1.0]heptane-2-carboxylate (CAS 286-25-9)
- 1-Allyl-5-(4-chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 338423-51-1)
- Cyclohexyl 4-bromo-2-ethoxybenzamide (CAS 1261895-34-4)
- 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-2-fluoro-2-methylpropane-1-sulfonyl chloride (CAS 1909314-21-1)
- 2-Amino-2-cyclopropylacetonitrile hydrochloride (CAS 381241-00-5)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
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