5-(Difluoromethyl)-2-(methylthio)pyrimidin-4-amine CAS 2090187-83-8
| CAS No. | 2090187-83-8 |
| Molecular Formula | C6H7F2N3S |
| Molecular Weight | 191.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(Difluoromethyl)-2-(methylthio)pyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-(Difluoromethyl)-2-(methylthio)pyrimidin-4-amine (CAS 2090187-83-8) is a high-purity analytical reference standard with the molecular formula C6H7F2N3S and a molecular weight of 191.20 g/mol.
The molecular framework of 5-(Difluoromethyl)-2-(methylthio)pyrimidin-4-amine (C6H7F2N3S) is characterized by a nitrile group, sulfur-containing functionality, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H7F2N3S |
| Molecular Weight | 191.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
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Recommended Standards
- 5-(4-Fluorophenyl)-5-oxopentanenitrile (CAS 898767-06-1)
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- 5-Fluoro-2-(3-methyl-1H-pyrazol-1-yl)aniline (CAS 923945-91-9)
- BT2F-2Th26Br (CAS 1293389-31-7)
- 1-(5-Methylpyridazin-3-yl)ethan-1-ol (CAS 2833706-78-6)
- 2-Methylquinoline-7-boronic acid pinacol ester, >97% (CAS 939052-79-6)
- 2-(p-Tolyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS 1177481-73-0)
- Rosuvastatin Impurity 140 (CAS 154026-92-3)
- 6-Methylpyrazolo[1,5-a]pyrazine-2-carboxylic acid (CAS 2407726-42-3)
- 4-[(dimethylamino)methyl]thiophene-2-carbaldehyde (CAS 893745-77-2)
- 1,11-Dodecadien-3-ol (CAS 81943-76-2)
- Promethazine EP Impurity D (CAS 7640-51-9)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
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