6-(3-Aminophenyl)piperidin-2-one CAS 2090446-29-8
| CAS No. | 2090446-29-8 |
| Molecular Formula | C11H14N2O |
| Molecular Weight | 190.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(3-Aminophenyl)piperidin-2-one.
6-(3-Aminophenyl)piperidin-2-one (CAS 2090446-29-8) is a high-purity analytical reference standard with the molecular formula C11H14N2O and a molecular weight of 190.24 g/mol.
The molecular framework of 6-(3-Aminophenyl)piperidin-2-one (C11H14N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14N2O |
| Molecular Weight | 190.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Aminophenyl Standards
- 2-(3-Aminophenyl)-n-cyclopropylacetamide (CAS 1018525-62-6)
- 1-(3-Aminophenyl)-5-methylpyrrolidin-2-one (CAS 1033693-04-7)
- n-(4-Aminophenyl)-n-methylcyclopropanecarboxamide (CAS 1092305-17-3)
- N-(4-Aminophenyl)-2-cyclopropylacetamide (CAS 1186377-98-9)
- 1-(4-Aminophenyl)-5-methylpyrrolidin-2-one (CAS 13691-28-6)
- 1-(2-Aminophenyl)piperidin-2-one (CAS 167864-96-2)
- 1-(4-Aminophenyl)-4-piperidinone (CAS 170011-70-8)
- (4-Aminophenyl)-pyrrolidin-1-ylmethanone (CAS 56302-41-1)
Recommended Standards
- 6-(2-Methylallyl)-2,3-dihydrobenzo[b][1,4]dioxine (CAS 951887-66-4)
- 6-(Piperidin-1-yl)picolinaldehyde (CAS 859850-71-8)
- 5-Phenylpyrrolidine-2-carboxamide (CAS 945-70-0)
- 6-(Piperidin-1-yl)pyridine-3-carbaldehyde (CAS 241816-11-5)
- 4-Amino-N-methylpiperidine-1-carbothioamide (CAS 1158944-68-3)
- 2-Methyl-2-(naphthalen-1-yl)oxirane (CAS 159805-33-1)
- 2-Methyl-6-(3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl)phenol (CAS 1550662-56-0)
- 2-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetyl)-N-phenylhydrazine-1-carbothioamide (CAS 338979-13-8)
- 1-(3,5-Dimethyl-4-(piperidin-1-ylsulfonyl)-1H-pyrazol-1-yl)ethan-1-one (CAS 1019105-78-2)
- 4-(4-Methoxyphenyl)-1-sulfanyl-4h,5h-[1,2,4]triazolo[4,3-a]quinazolin-5-one (CAS 345936-00-7)
- 1-Allyl-3-(2,4-dichlorophenyl)urea (CAS 37919-97-4)
- 2-Phenylethyl 1-thio-beta-D-glucopyranoside (CAS 800376-82-3)
- 3-Amino-1-isopropyl-5-methylindolin-2-one (CAS 1214054-27-9)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
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