1-Bromo-3-chloro-5-(difluoromethyl)-2-methoxybenzene CAS 2091157-62-7
| CAS No. | 2091157-62-7 |
| Molecular Formula | C8H6BrClF2O |
| Molecular Weight | 271.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Bromo-3-chloro-5-(difluoromethyl)-2-methoxybenzene (CAS 2091157-62-7) is a high-purity analytical reference standard with the molecular formula C8H6BrClF2O and a molecular weight of 271.49 g/mol.
Based on its molecular formula C8H6BrClF2O, 1-Bromo-3-chloro-5-(difluoromethyl)-2-methoxybenzene contains a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 271.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-Bromo-3-chloro-5-(difluoromethyl)-2-methoxybenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrClF2O |
| Molecular Weight | 271.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- 4-bromo-2-(chloromethyl)-1-(difluoromethoxy)benzene (CAS 1039329-39-9)
- 4-Bromo-1-chloro-2-(2,2-difluoroethoxy)benzene (CAS 1343731-27-0)
- 1-Bromo-2-(2-chloroethoxy)-3,5-difluorobenzene (CAS 175203-19-7)
- (2-Bromo-3-chloro-6-(difluoromethyl)pyridin-4-yl)methanamine (CAS 1803690-34-7)
- (5-Bromo-3-chloro-2-(difluoromethyl)pyridin-4-yl)methanamine (CAS 1803690-45-0)
- 3-Bromo-4-(chloromethyl)-6-(difluoromethyl)pyridin-2-amine (CAS 1804694-04-9)
- 5-Bromo-3-(chloromethyl)-6-(difluoromethyl)pyridin-2-amine (CAS 1804694-25-4)
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Recommended Standards
- 2-(4-Bromo-2-chlorophenyl)-2,2-difluoroethanol (CAS 1823998-15-7)
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- 4-Bromo-3-(chloromethyl)-5-(difluoromethyl)pyridin-2-amine (CAS 1806887-10-4)
- 2-Bromo-3-chloronaphthalene-1,4-dione (CAS 88645-45-8)
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- tert-Butyl 3-((3-fluorophenyl)amino)pyrrolidine-1-carboxylate (CAS 887578-60-1)
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