8-Hydroxyisoquinoline-3-carboxamide CAS 2092486-00-3
| CAS No. | 2092486-00-3 |
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Hydroxyisoquinoline-3-carboxamide.
CATO supplies 8-Hydroxyisoquinoline-3-carboxamide (CAS 2092486-00-3), a certified reference material (molecular formula C10H8N2O2, MW 188.18 g/mol) for analytical method development and quality control.
8-Hydroxyisoquinoline-3-carboxamide (C10H8N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Hydroxyisoquinoline-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Hydroxyisoquinoline Standards
- N-Hydroxyisoquinoline-1-carboxamide (CAS 1086392-60-0)
- 5-Hydroxyisoquinoline-1-carboxamide (CAS 136481-42-0)
- N-Hydroxyisoquinoline-6-carboxamide (CAS 1368396-43-3)
- N’-Hydroxyisoquinoline-1-carboximidamide (CAS 17954-33-5)
- 1-Hydroxyisoquinoline-8-carboxylicacid (CAS 116409-31-5)
- 5-Hydroxyisoquinoline-6-carboxylic acid (CAS 1332370-65-6)
- 3-hydroxyisoquinoline-8-carboxylic acid (CAS 1337881-30-7)
- 7-Hydroxyisoquinoline-4-carboxylic acid (CAS 1378839-26-9)
Recommended Standards
- 8-aminoquinoline-7-carboxylic acid (CAS 914208-05-2)
- 8-Hydroxyquinoline-2-carbaldehyde oxime (CAS 5603-22-5)
- 8-Aminoquinoline-5-carboxylic acid (CAS 860205-79-4)
- 8-Hydroxyquinoline-2-carboxamide (CAS 6759-79-1)
- 1-(2-Chloropyridin-4-yl)-5-cyclohexylpentan-1-one (CAS 898785-51-8)
- 2-((1,3,4-Thiadiazol-2-yl)thio)-1-(thiophen-2-yl)ethan-1-one (CAS 876934-59-7)
- 3-Isopropoxy-N-[2-(2-methoxyphenoxy)propyl]aniline (CAS 1040684-34-1)
- (3-Chlorophenyl)(4-pentylphenyl)methanone (CAS 64358-14-1)
- 2-[2-(difluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 879275-72-6)
- Chloride[(1,2,5,6-η)-1,5-cyclooctadiene][N-(2-pyridinylmethylene)methanamine-N,N']rhodium(1+) (CAS 98716-29-1)
- Methyl 2-amino-3-(4-bromo-1h-indol-3-yl)propanoate hydrochloride (CAS 1423024-60-5)
- 8-Methyl-4-(3,4,5-trimethoxybenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-97-2)
- Rel-(3R,5R)-5-methylpiperidine-3-carboxylic acid (CAS 110287-72-4)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com