(S)-5-(tert-butoxycarbonyl)-5-azaspiro[2.4]Heptane-4-carboxylic acid CAS 209269-08-9
| CAS No. | 209269-08-9 |
| Molecular Formula | C12H19NO4 |
| Molecular Weight | 241.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(S)-5-(tert-butoxycarbonyl)-5-azaspiro[2.4]Heptane-4-carboxylic acid (CAS 209269-08-9), molecular formula C12H19NO4 and molecular weight 241.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (S)-5-(tert-butoxycarbonyl)-5-azaspiro[2.4]Heptane-4-carboxylic acid (C12H19NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H19NO4 |
| Molecular Weight | 241.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (S)-4-Boc-4-azaspiro[2.4]heptane-5-carboxylic Acid (CAS 1984825-25-3)
- (S,E)-1-(tert-butoxycarbonyl)-4-ethylidenepyrrolidine-2-carboxylic acid (CAS 2411422-23-4)
- (S)-(1-Benzyl-4,4-difluoropiperidin-3-yl)methanol (CAS 2378854-78-3)
- (Z)-tert-Butyl 3-(2-methoxy-2-oxoethylidene)pyrrolidine-1-carboxylate (CAS 441773-67-7)
- 5,7-Dichloro-3-cyclobutylpyrazolo[1,5-a]pyrimidine (CAS 1824297-28-0)
- O,O 2-Bis(2-aminoethyl)hexaethylene Glycol (CAS 332941-25-0)
- n-(Bicyclo[2.2.1]hept-5-en-2-ylmethyl)pentan-3-amine (CAS 1218189-07-1)
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- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
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