4-(2,2-Difluorocyclopropyl)piperidine CAS 2092725-85-2
| CAS No. | 2092725-85-2 |
| Molecular Formula | C8H13F2N |
| Molecular Weight | 161.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-(2,2-Difluorocyclopropyl)piperidine (CAS 2092725-85-2), a certified reference material (molecular formula C8H13F2N, MW 161.19 g/mol) for analytical method development and quality control.
The molecular framework of 4-(2,2-Difluorocyclopropyl)piperidine (C8H13F2N) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-(2,2-Difluorocyclopropyl)piperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H13F2N |
| Molecular Weight | 161.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorocyclopropyl Standards
- 5-(2,2-Difluorocyclopropyl)-1h-pyrazol-3-amine (CAS 1186609-07-3)
- ethyl 2-(2,2-difluorocyclopropyl)acetate (CAS 1393553-89-3)
- 1-(2,2-Difluorocyclopropyl)Ethyl Acetate (CAS 509072-71-3)
- 1-(2,2-Difluorocyclopropyl)-4-methylbenzene (CAS 54672-44-5)
- (2,2-Difluorocyclopropyl)benzene (CAS 13343-40-3)
- 2-(2,2-Difluorocyclopropyl)aniline (CAS 1892415-35-8)
- 3-(2,2-Difluorocyclopropyl)aniline (CAS 928248-52-6)
- 4-(2,2-Difluorocyclopropyl)aniline (CAS 35694-68-9)
Recommended Standards
- 2,2-Difluoro-6-azaspiro[3.5]nonane (CAS 2138068-73-0)
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- 2,2-Difluoro-5-azaspiro[3.5]Nonane (CAS 2287861-88-3)
- 7,7-Difluoro-2-azaspiro[3.5]Nonane (CAS 2169167-41-1)
- ethyl 5-amino-2-bromo-thiazole-4-carboxylate (CAS 1228281-54-6)
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- 3-(1H-benzo[d][1,2,3]triazol-1-yl)propan-1-amine hydrochloride (CAS 2928-72-5)
- ethyl (5Z,8Z,11Z,14Z,17E)-icosa-5,8,11,14,17-pentaenoate (CAS 125827-48-7)
- 2-(Benzo[4,5]thiazolo[2,3-c][1,2,4]triazol-3-ylthio)acetic acid (CAS 114722-63-3)
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