[2-Chloro-5-(pyridin-3-ylmethoxy)-4-(trifluoromethoxy)phenyl]boronic acid CAS 2096339-46-5
| CAS No. | 2096339-46-5 |
| Molecular Formula | C13H10BClF3NO4 |
| Molecular Weight | 347.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
[2-Chloro-5-(pyridin-3-ylmethoxy)-4-(trifluoromethoxy)phenyl]boronic acid (CAS 2096339-46-5), molecular formula C13H10BClF3NO4 and molecular weight 347.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of [2-Chloro-5-(pyridin-3-ylmethoxy)-4-(trifluoromethoxy)phenyl]boronic acid (C13H10BClF3NO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures [2-Chloro-5-(pyridin-3-ylmethoxy)-4-(trifluoromethoxy)phenyl]boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10BClF3NO4 |
| Molecular Weight | 347.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- Methyl 2-oxo-5-(phenylthio)-1,2-dihydropyridine-3-carboxylate (CAS 95797-14-1)
- Fezolinetant Impurity 35 (CAS CATO-C4X-327035)
- 2-((2-Benzoyl-4-chlorophenyl)(cyclopropylmethyl)amino)-2-oxoacetic acid (CAS 33453-17-7)
- Ethyl 6-(2,6-difluorophenyl)-6-oxohexanoate (CAS 898753-26-9)
- 4-(4-(Tert-butyl)phenyl)-2,2-dimethyl-4-oxobutanoic acid (CAS 951893-29-1)
- 2-FLUORO-1-METHOXY-4-NITROBENZENE 2-FLUORO-4-NITROANISOLE 3-FLUORO-4-METHOXYNITROBENZENE 455-93-6 AS04146 BENZENE, 2-FLUORO-1-METHOXY-4-NITRO- PHARMABRIDGE P-3000 (CAS 455-93-6)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
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