(6-Chloro-2-(trifluoromethyl)pyridin-3-yl)boronic acid CAS 2096339-76-1
| CAS No. | 2096339-76-1 |
| Molecular Formula | C6H4BClF3NO2 |
| Molecular Weight | 225.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (6-Chloro-2-(trifluoromethyl)pyridin-3-yl)boronic acid.
CATO supplies (6-Chloro-2-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2096339-76-1), a certified reference material (molecular formula C6H4BClF3NO2, MW 225.36 g/mol) for analytical method development and quality control.
(6-Chloro-2-(trifluoromethyl)pyridin-3-yl)boronic acid (C6H4BClF3NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4BClF3NO2 |
| Molecular Weight | 225.36 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- (6-Chloro-4-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 1217500-87-2)
- (6-Chloro-4-(trifluoromethyl)pyridin-2-yl)boronic acid (CAS 1217500-88-3)
- (2-Chloro-6-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 1446486-10-7)
- (3-Chloro-2-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 2096331-34-7)
- [5-Chloro-2-(trifluoromethyl)pyridin-4-yl]boronic acid (CAS 2225174-70-7)
- [6-Chloro-5-(trifluoromethyl)pyridin-3-yl]boronic acid (CAS 2096336-32-0)
- 2-Chloro-5-(trifluoromethyl)pyridine-3-boronic Acid (CAS 536693-96-6)
- 2-Chloro-6-(trifluoromethyl)pyridine-3-boronic Acid (CAS 205240-63-7)
Recommended Standards
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- 2-((Trimethylsilyl)ethynyl)quinoline (CAS 86521-07-5)
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