(3R,4R)-1-(tert-butoxycarbonyl)-4-(2,4-difluorophenyl)-3-fluoropyrrolidine-3-carboxylic acid CAS 2098740-27-1
| CAS No. | 2098740-27-1 |
| Molecular Formula | C16H18F3NO4 |
| Molecular Weight | 345.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (3R,4R)-1-(tert-butoxycarbonyl)-4-(2,4-difluorophenyl)-3-fluoropyrrolidine-3-carboxylic acid (CAS 2098740-27-1), a certified reference material (molecular formula C16H18F3NO4, MW 345.31 g/mol) for analytical method development and quality control.
(3R,4R)-1-(tert-butoxycarbonyl)-4-(2,4-difluorophenyl)-3-fluoropyrrolidine-3-carboxylic acid (C16H18F3NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures (3R,4R)-1-(tert-butoxycarbonyl)-4-(2,4-difluorophenyl)-3-fluoropyrrolidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H18F3NO4 |
| Molecular Weight | 345.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2R,3R,4S,5R,6S)-2-(azidomethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 21893-05-0)
- 1,3-Bis((3-chlorophenyl)thio)propan-2-ol (CAS 400081-05-2)
- (2R,3R,4S,5R)-2-(6-Hydroxy-2-(pyridin-3-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 88868-68-2)
- 1,3-Bis[(2-chlorophenyl)sulfanyl]propan-2-ol (CAS 400081-06-3)
- Methyl 3-(2,5-dichlorophenyl)-5-methylisoxazole-4-carboxylate (CAS 4402-80-6)
- 5-Methyl-1-(3-nitrophenyl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 929975-73-5)
- (S)-1-(3-(Cyclopropylamino)pyrrolidin-1-yl)ethanone (CAS 1353998-27-2)
- 2,3-Dichloro-5-iodoaniline (CAS 1803823-49-5)
- 3-Amino-4-chloro-N-(tetrahydro-2H-pyran-4-ylmethyl)benzenesulfonamide (CAS 1220019-16-8)
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- 2-Hydroxy-2,3-dihydro-1H-indene-5,6-dicarboxylic acid (CAS 2616551-92-7)
- GSK 1904529A (CAS 1089283-49-7)
- Ornidazole Impurity 95 (CAS CATO-C4X-133195)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com