tert-Butyl (4s,5s)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)piperidine-1-carboxylate racemic CAS 2101206-70-4
| CAS No. | 2101206-70-4 |
| Molecular Formula | C11H19F2NO4 |
| Molecular Weight | 267.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl (4s,5s)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)piperidine-1-carboxylate racemic (CAS 2101206-70-4), molecular formula C11H19F2NO4 and molecular weight 267.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of tert-Butyl (4s,5s)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)piperidine-1-carboxylate racemic (C11H19F2NO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures tert-Butyl (4s,5s)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)piperidine-1-carboxylate racemic under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H19F2NO4 |
| Molecular Weight | 267.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl (4S,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)piperidine-1-carboxylate (CAS 2165779-31-5)
- Risperidone Impurity 19 (CAS 84162-82-3)
- Risperidone RC 2 (CAS 25519-77-1)
- Olaquindox-d4 (CAS 1189487-82-8)
- 5-(2-hydroxyethyl)-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide (CAS 953882-05-8)
- 4-(Cyclopropylmethoxy)-3-methylbenzoic Acid (CAS 1252903-16-4)
- N-(6-Amino-1-(4-fluorophenyl)-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-di-tert-butyl-4-hydroxybenzamide (CAS 176378-79-3)
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- N-Benzyl-1-(p-tolyl)-1H-1,2,3-triazole-4-carboxamide (CAS 951597-72-1)
- Neuropeptide W-23 (rat) (CAS 383415-89-2)
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