tert-Butyl 4-(6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate CAS 2101287-23-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2101287-23-2
Molecular FormulaC17H20ClFN4O2
Molecular Weight366.82 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl 4-(6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate CAS 2101287-23-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl 4-(6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate.

tert-Butyl 4-(6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate (CAS 2101287-23-2) is a high-purity analytical reference standard with the molecular formula C17H20ClFN4O2 and a molecular weight of 366.82 g/mol.

The molecular framework of tert-Butyl 4-(6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate (C17H20ClFN4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures tert-Butyl 4-(6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC17H20ClFN4O2
Molecular Weight366.82 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1997
Halogen ContentF/Cl-containing
Nitrogen Atoms4

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