1-Chloro-2-(methylsulfonyl)-4-nitrobenzene CAS 21081-74-3
| CAS No. | 21081-74-3 |
| Molecular Formula | C7H6ClNO4S |
| Molecular Weight | 235.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Chloro-2-(methylsulfonyl)-4-nitrobenzene (CAS 21081-74-3), molecular formula C7H6ClNO4S and molecular weight 235.64 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-Chloro-2-(methylsulfonyl)-4-nitrobenzene (C7H6ClNO4S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 235.64 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 1-Chloro-2-(methylsulfonyl)-4-nitrobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6ClNO4S |
| Molecular Weight | 235.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 2-Chloro-7-(difluoromethoxy)benzo[d]thiazole (CAS 1261629-26-8)
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- 2-Chloro-6-(difluoromethoxy)benzo[d]thiazole (CAS 1261786-73-5)
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- 5-(4-Chloro-2-fluorophenyl)nicotinaldehyde (CAS 1346691-91-5)
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Recommended Standards
- (R)-3-(Difluoromethoxy)pyrrolidine-1-sulfonyl chloride (CAS 2754410-06-3)
- 1-Chloro-4-((nitromethyl)sulfonyl)benzene (CAS 66073-97-0)
- (6-Chloropyridin-3-yl)(4-fluorophenyl)methanone (CAS 80099-93-0)
- 1-Chloro-4-(methylsulfonyl)-2-nitrobenzene (CAS 97-07-4)
- Ethyl 2-(3-bromo-4-methoxyphenyl)-2-oxoacetate (CAS 1226321-02-3)
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- N-(2-chloro-5-fluoro-4-pyrimidinyl)-N-ethylamine (CAS 321529-80-0)
- 6-Bromonaphthalen-2-yl trifluoromethanesulfonate (CAS 151600-02-1)
- 8-chloro-6-methyl-1,7-naphthyridine (CAS 1250444-30-4)
- (5-(3-Chlorophenyl)-1H-imidazol-2-yl)methanamine (CAS 944897-81-8)
- 5-Ethynyl-1H-pyrrolo[2,3-b]pyridine (CAS 1207351-16-3)
- 2-((5-((4-Methoxybenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N-(4-sulfamoylphenyl)acetamide (CAS 499103-73-0)
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- (Leu31,Pro3?)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 125580-28-1)
Why CATO?
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