1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidine-3-carboxylic acid CAS 2108830-91-5
| CAS No. | 2108830-91-5 |
| Molecular Formula | C8H12N4O2S |
| Molecular Weight | 228.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidine-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidine-3-carboxylic acid (CAS 2108830-91-5), molecular formula C8H12N4O2S and molecular weight 228.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidine-3-carboxylic acid (C8H12N4O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12N4O2S |
| Molecular Weight | 228.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-N-cyclopropyl-4-hydroxybenzene-1-sulfonamide (CAS 1036458-44-2)
- 2-(3-Amino-4-hydroxyphenyl)-1,2-thiazolidine-1,1-dione (CAS 1147800-90-5)
- 2-Amino-N-methyl-4-(methylsulfonyl)benzamide (CAS 1201935-75-2)
- 4-Amino-2-cyclopropoxybenzenesulfonamide (CAS 1243458-68-5)
- 2-((4-Amino-6-hydroxypyrimidin-2-yl)thio)-N,N-dimethylacetamide (CAS 571922-95-7)
- 2-(5-Amino-[1,3,4]thiadiazol-2-yl)-1-morpholin-4-yl-ethanone (CAS 714278-21-4)
- 2-Amino-4h-thieno[2,3-c]chromene-1-carbonitrile (CAS 907962-53-2)
- 4-Amino-6-phenyl-2-thioxo-1,2-dihydropyrimidine-5-carbonitrile (CAS 75129-07-6)
Recommended Standards
- 1-(1,3-Benzothiazol-2-yl)-1h-pyrrole-2-carbaldehyde (CAS 383135-58-8)
- 1-Phenyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidine-4-thione (CAS 6014-07-9)
- [(5-Ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetic acid (CAS 347343-04-8)
- 2-((4,6-Diaminopyrimidin-2-yl)thio)butanoic acid (CAS 436088-61-8)
- 2-((((Benzyloxy)carbonyl)amino)methyl)-5-methyloxazole-4-carboxylic acid (CAS 683815-52-3)
- Boc-trans-DL-β-Pro-4-(4-methoxyphenyl)-OH (CAS 1000415-75-7)
- 2-(Ethylthio)-5-nitropyrimidin-4(1H)-one (CAS 76592-09-1)
- Ethyl cinnoline-3-carboxylate (CAS 67080-45-9)
- 2-chloro-5-fluoro-[1,2,4]triazolo[1,5-a]pyridine (CAS 1935530-29-2)
- 1-[2-fluoro-5-(trifluoromethyl)phenyl]guanidine hydrochloride (CAS 1803587-42-9)
- (3,3,3-Trifluoroprop-1-en-1-yl)benzene (CAS 705-89-5)
- 4-Amino-5-(2-(methylthio)ethyl)-4H-1,2,4-triazole-3-thiol (CAS 1172536-38-7)
- Cyclobutyl 2-(3-pyrrolinomethyl)phenyl ketone (CAS 898763-90-1)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com