(4-(2-Methoxyphenyl)piperazin-1-yl)(4-nitrophenyl)methanone CAS 21091-99-6

Purity 97%+In StockPharmaceutical Standards
CAS No.21091-99-6
Molecular FormulaC18H19N3O4
Molecular Weight341.36 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(4-(2-Methoxyphenyl)piperazin-1-yl)(4-nitrophenyl)methanone CAS 21091-99-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4-(2-Methoxyphenyl)piperazin-1-yl)(4-nitrophenyl)methanone.

CATO supplies (4-(2-Methoxyphenyl)piperazin-1-yl)(4-nitrophenyl)methanone (CAS 21091-99-6), a certified reference material (molecular formula C18H19N3O4, MW 341.36 g/mol) for analytical method development and quality control.

The molecular framework of (4-(2-Methoxyphenyl)piperazin-1-yl)(4-nitrophenyl)methanone (C18H19N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H19N3O4
Molecular Weight341.36 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963
Nitrogen Atoms3

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