Tert-butyl 3,6-dichloropicolinate CAS 211122-64-4
| CAS No. | 211122-64-4 |
| Molecular Formula | C10H11Cl2NO2 |
| Molecular Weight | 248.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tert-butyl 3,6-dichloropicolinate.
Tert-butyl 3,6-dichloropicolinate (CAS 211122-64-4) is a high-purity analytical reference standard with the molecular formula C10H11Cl2NO2 and a molecular weight of 248.11 g/mol.
The molecular framework of Tert-butyl 3,6-dichloropicolinate (C10H11Cl2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Tert-butyl 3,6-dichloropicolinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11Cl2NO2 |
| Molecular Weight | 248.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl 2,6-Dichloropyridine-4-carboxylate (CAS 75308-46-2)
- tert-Butyl 4,5-dichloropicolinate (CAS 2089301-03-9)
- Propyl (3,5-dichlorophenyl)carbamate (CAS 25138-13-0)
- Ziprasidone impurity 52 (CAS CATO-C4X-124052)
- (S)-N-Cyclopropyl-N-(pyrrolidin-2-ylmethyl)acetamide (CAS 1354009-83-8)
- 1-(3-Chlorobenzyl)-5-ethyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1266837-89-1)
- 2-(2,5-Dichlorophenyl)oxirane (CAS 2783-27-9)
- Propan-2-yl 2-(4-benzylpiperazin-1-yl)pyridine-3-carboxylate (CAS 338792-73-7)
- (1-(Furan-2-ylmethyl)pyrrolidin-3-yl)methanol (CAS 1017429-92-3)
- 2-(oxolan-3-yl)acetonitrile (CAS 476415-60-8)
- 2-((8-Bromo-2,3,4,5-tetrahydrobenzo[b]oxepin-5-yl)oxy)ethan-1-ol (CAS 2091203-48-2)
- Glasdegib maleate, >98% (HPLC) (CAS 2030410-25-2)
- Butane-1,4-disulfonyl dichloride (CAS 3079-82-1)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com