Methyl 5-chloro-2-fluoro-4-methoxybenzoate CAS 211172-73-5
| CAS No. | 211172-73-5 |
| Molecular Formula | C9H8ClFO3 |
| Molecular Weight | 218.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 5-chloro-2-fluoro-4-methoxybenzoate (CAS 211172-73-5), molecular formula C9H8ClFO3 and molecular weight 218.61 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 5-chloro-2-fluoro-4-methoxybenzoate (C9H8ClFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Methyl 5-chloro-2-fluoro-4-methoxybenzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8ClFO3 |
| Molecular Weight | 218.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
- Methyl 4-chloro-3-fluoro-2-methoxybenzoate (CAS 2114129-19-8)
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- 7H-Purine-6-sulfonyl chloride (CAS 1248933-54-1)
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- N2-Ethyl-N2-isobutylthiazole-2,4-diamine (CAS 1365939-37-2)
- 5-Methyl-N-(piperidin-4-yl)isoxazole-3-carboxamide hydrochloride (CAS 1209330-86-8)
- 2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine (CAS 237402-29-8)
- 7-Hydroxy-5-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 1713639-47-4)
- 3-methyl-2-(propan-2-yl)butanal (CAS 35155-64-7)
- Ethyl 2-methyl-4-(2-nitrophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate (CAS 176383-19-0)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
Why CATO?
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