1-(4-Aminobenzyl)piperidin-2-one CAS 21172-66-7
| CAS No. | 21172-66-7 |
| Molecular Formula | C12H16N2O |
| Molecular Weight | 204.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(4-Aminobenzyl)piperidin-2-one (CAS 21172-66-7), molecular formula C12H16N2O and molecular weight 204.27 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, 1-(4-Aminobenzyl)piperidin-2-one is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 204.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-Aminobenzyl)piperidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O |
| Molecular Weight | 204.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Related Aminobenzyl Standards
- 5-(4-Aminobenzyl)-1,3,4-thiadiazol-2-amine (CAS 890095-77-9)
- N-(3-aminobenzyl)-3-methoxypropanamide (CAS 1248725-35-0)
- N-(3-Aminobenzyl)methanesulfonamide (CAS 856193-46-9)
- Ethyl (2-aminobenzyl)phosphinate (CAS 31238-61-6)
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- 4-(4-Aminobenzyl)-N-methylaniline (CAS 26628-67-1)
Recommended Standards
- 1-(4-Amino-3,5-dimethylphenyl)pyrrolidin-2-one (CAS 924830-53-5)
- 1-(4-Aminomethyl-benzyl)-pyrrolidin-2-one (CAS 953752-30-2)
- 1-(4-Amino-2-methylphenyl)piperidin-2-one (CAS 443999-53-9)
- 1-(4-Methoxy-2-methylphenyl)pyrrolidin-2-imine (CAS 786700-83-2)
- 6-(Aminomethyl)-3-(difluoromethyl)-5-(trifluoromethoxy)pyridin-2-amine (CAS 1804608-79-4)
- 5-(5-Iodo-1H-indazol-1-yl)pyridin-2(1H)-one (CAS 1893415-30-9)
- 5-(3-Nitrophenyl)-1,2-oxazole (CAS 126633-02-1)
- 1-(4-Nitrophenyl)-1h-1,2,3-triazole-4-carbaldehyde (CAS 113934-26-2)
- 3-bromo-2,6-dimethylaniline (CAS 53874-26-3)
- 5-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxamide (CAS 1936355-36-0)
- 4-(2-(4-Bromophenoxy)acetamido)butanoic acid (CAS 1098393-24-8)
- Deoxycholic acid Impurity 42 (CAS CATO-C4X-335942)
- L-Homocysteine Thiolactone (CAS 2338-04-7)
- Neuropeptide Y (1-24) amide (human, rat) (CAS 131448-51-6)
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