(R)-3,3-Difluoro-5-(hydroxymethyl)dihydrofuran-2(3H)-one CAS 211807-33-9
| CAS No. | 211807-33-9 |
| Molecular Formula | C5H6F2O3 |
| Molecular Weight | 152.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(R)-3,3-Difluoro-5-(hydroxymethyl)dihydrofuran-2(3H)-one (CAS 211807-33-9), molecular formula C5H6F2O3 and molecular weight 152.10 g/mol, is a CATO reference standard with documented purity and traceability.
(R)-3,3-Difluoro-5-(hydroxymethyl)dihydrofuran-2(3H)-one (C5H6F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6F2O3 |
| Molecular Weight | 152.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2017 |
| Halogen Content | F-containing |
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Recommended Standards
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- Methyl 3-(2,3-dimethylthiomorpholino)-2-methylpropanoate (CAS 1598356-14-9)
- 4-Bromo-3-(4-methylphenyl)propiophenone (CAS 898768-71-3)
- PD36FU2WGY 38205-60-6 2,4-Dimethyl-5-acetylthiazole 1-(2,4-Dimethylthiazol-5-yl)ethan-1-one Ethanone, 1-(2,4-dimethyl-5-thiazolyl)- 5-Acetyl-2,4-dimethylthiazole 1-(2,4-Dimethyl-5-thiazolyl)ethanone 2,4-Dimethyl-5-thiazoyl methyl ketone EINECS 253-826-0 FEMA No. 3267 Ketone, 2,4-dimethyl-5-thiazolyl methyl UNII-PD36FU2WGY (CAS 38205-60-6)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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