4-Chloro-2,3-difluoro-5-methoxyphenylboronic acid pinacol ester CAS 2121511-96-2
| CAS No. | 2121511-96-2 |
| Molecular Formula | C13H16BClF2O3 |
| Molecular Weight | 304.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-2,3-difluoro-5-methoxyphenylboronic acid pinacol ester.
4-Chloro-2,3-difluoro-5-methoxyphenylboronic acid pinacol ester (CAS 2121511-96-2), molecular formula C13H16BClF2O3 and molecular weight 304.53 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Chloro-2,3-difluoro-5-methoxyphenylboronic acid pinacol ester (C13H16BClF2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.5, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 304.53 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-2,3-difluoro-5-methoxyphenylboronic acid pinacol ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16BClF2O3 |
| Molecular Weight | 304.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-5-fluoro-3-iodo-1H-pyrrolo[2,3-b]pyridine (CAS 1228665-90-4)
- 4-Chloro-5-fluoro-6-iodo-1H-pyrrolo[2,3-b]pyridine (CAS 1228665-91-5)
- 2-(4-Chloro-3-difluoromethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1310949-73-5)
- 2-(3-Chloro-4-(difluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1310949-92-8)
- 2-(5-Chloro-2-(difluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2609682-60-0)
- 2-chloro-3-iodo-5-methyl-1,6-naphthyridine (CAS 1407521-91-8)
- 4-Chloro-8-iodo-2-methylquinazoline (CAS 1934474-78-8)
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Recommended Standards
- Ethyl 2-bromo-5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 2612482-15-0)
- 2-(3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)acetic acid (CAS 2387596-07-6)
- Ethyl 8-bromo-2-chloroimidazo[1,2-b]pyridazine-7-carboxylate (CAS 2434602-65-8)
- Cetylpyridinium (CAS 7773-52-6)
- Taurine bromamine (CAS 52316-57-1)
- 2-(5-Bromopyridin-3-yl)-2-methylpropanal (CAS 1404367-22-1)
- 3-Methoxy-1,7-naphthyridin-8(7H)-one (CAS 1569695-13-1)
- 5-Azaspiro[2.6]Nonan-4-one (CAS 2138051-83-7)
- Ethyl (E)-3-(2-fluorophenyl)acrylate (CAS 89760-42-9)
- 5-((tert-Butoxycarbonyl)amino)furan-2-carboxylic acid (CAS 1211512-16-1)
- Tert-butyl 7-benzyl-9-(hydroxymethyl)-2,7-diazaspiro[4.4]Nonane-2-carboxylate (CAS 1823258-46-3)
- 6-(Morpholinosulfonyl)quinoline-4-carboxylic acid (CAS 1086393-16-9)
- 2-(3,5-Dimethyl-1-propyl-1H-pyrazol-4-yl)acetic acid (CAS 1007460-73-2)
- Insulin Glargine (CAS 160337-95-1)
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