2,5-Difluoro-4-ethoxyphenylboronic acid pinacol ester CAS 2121512-38-5
| CAS No. | 2121512-38-5 |
| Molecular Formula | C14H19BF2O3 |
| Molecular Weight | 284.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,5-Difluoro-4-ethoxyphenylboronic acid pinacol ester (CAS 2121512-38-5), molecular formula C14H19BF2O3 and molecular weight 284.11 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2,5-Difluoro-4-ethoxyphenylboronic acid pinacol ester is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,5-Difluoro-4-ethoxyphenylboronic acid pinacol ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H19BF2O3 |
| Molecular Weight | 284.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 1-(3,5-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol (CAS 1586045-19-3)
- 1-[2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanol (CAS 1858215-82-3)
- (2,3-Difluoro-4-nonylphenyl)boronic acid (CAS 126334-38-1)
- 2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid (CAS 1008119-07-0)
- 2,5-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid (CAS 1383968-46-4)
- 2-(2,2-Difluoro-2h-1,3-benzodioxol-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628572-83-7)
- 2-(2,2-Difluoro-2h-1,3-benzodioxol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 517874-23-6)
- 3,4-Difluoro-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid (CAS 2377606-94-3)
Recommended Standards
- 2-(5-Bromo-2-ethoxy-4-formylphenoxy)acetonitrile (CAS 832673-70-8)
- 2-Bromo-4-cyano-6-ethoxyphenyl acetate (CAS 515831-66-0)
- 2-(4-Ethoxy-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2282635-46-3)
- 2-Bromo-6,7-dimethoxyquinazolin-4-amine (CAS 65679-31-4)
- Ethyl 6,7-difluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 1470024-53-3)
- (S)-3,3'-Bis(3,5-dimethylphenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2,2'-naphthol (CAS 1402852-05-4)
- 4-Methylbenzofuran (CAS 5670-23-5)
- Oxadiazol Impurity 1 (CAS CATO-C4X-24001)
- Ac-Pro-Leu-Gly-OH (CAS 89626-38-0)
- tert-Butyl 7-fluoro-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate (CAS 1290627-44-9)
- (6-Fluoro-2-methoxypyridin-3-yl)boronic acid (CAS 1443380-14-0)
- 1-(4-Bromo-2,6-dichlorophenyl)-1H-pyrrole (CAS 219139-07-8)
- Benzenamine, 2-(bromomethyl)-5-chloro-, hydrobromide (1:1) (CAS 71693-08-8)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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