5-Chloro-2-fluoro-4-hydroxyphenylboronic acid pinacol ester CAS 2121513-66-2
| CAS No. | 2121513-66-2 |
| Molecular Formula | C12H15BClFO3 |
| Molecular Weight | 272.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-2-fluoro-4-hydroxyphenylboronic acid pinacol ester (CAS 2121513-66-2), molecular formula C12H15BClFO3 and molecular weight 272.51 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H15BClFO3, 5-Chloro-2-fluoro-4-hydroxyphenylboronic acid pinacol ester contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 272.51 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-2-fluoro-4-hydroxyphenylboronic acid pinacol ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15BClFO3 |
| Molecular Weight | 272.51 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
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