2-Chloro-5-fluoro-3-(trifluoromethyl)phenylboronic acid CAS 2121513-70-8
| CAS No. | 2121513-70-8 |
| Molecular Formula | C7H4BClF4O2 |
| Molecular Weight | 242.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 242.36 g/mol gives 2-Chloro-5-fluoro-3-(trifluoromethyl)phenylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-5-fluoro-3-(trifluoromethyl)phenylboronic acid (CAS 2121513-70-8) is a high-purity analytical reference standard with the molecular formula C7H4BClF4O2 and a molecular weight of 242.36 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Chloro-5-fluoro-3-(trifluoromethyl)phenylboronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-5-fluoro-3-(trifluoromethyl)phenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4BClF4O2 |
| Molecular Weight | 242.36 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl)boronic acid (CAS 2096342-38-8)
- 5-Chloro-2-fluoro-3-(trifluoromethyl)phenylboronic acid (CAS 2121513-80-0)
- 4-Chloro-5-iodo-1-methyl-1H-pyrazole (CAS 1516855-00-7)
- 4-Chloro-3-iodo-1-methyl-1H-pyrazole (CAS 1522902-68-6)
- 5-Chloro-3-iodo-1-methyl-1H-pyrazole (CAS 2585063-96-1)
- 5-Chloro-4-iodo-1-methyl-1H-pyrazole (CAS 2109554-73-4)
- (3-Chloro-2-morpholinopyridin-4-yl)boronic acid (CAS 957061-04-0)
- (4-Chloro-2-(cyclopentyloxy)pyrimidin-5-yl)boronic acid (CAS 2225172-44-9)
Recommended Standards
- 1-Butyl-4-phenylpiperidine-4-carbonitrile (CAS 42520-99-0)
- 3-(3-(Piperidin-1-yl)propyl)-1H-indole (CAS 98132-63-9)
- 1-Boc-N-propylpiperidin-4-amine (CAS 301225-58-1)
- 3-Allyl-8-benzyl-3,8-diazabicyclo[3.2.1]octane (CAS 415979-07-6)
- 5'-Methyl-4,6-diphenyl-2H-[1,2'-bipyridine]-2-thione (CAS 62219-35-6)
- 5-(3-Chlorophenyl)-1-hydroxy-3-phenylpyrazin-2(1H)-one (CAS 339030-55-6)
- 6-Chloro-3-hydroxybenzo[b]thiophene-2-carboxylic acid (CAS 1393803-55-8)
- Clophedianol (CAS 791-35-5)
- n-(Cyclopropylmethyl)-3-(1-methyl-1h-tetrazol-5-yl)aniline (CAS 1153008-38-8)
- 1-Chloro-3-(2,2,2-trifluoroethoxy)propane (CAS 1016495-32-1)
- 5-((1H-pyrrol-2-yl)methyl)-1H-pyrrole-2-carbaldehyde (CAS 36746-27-7)
- 2,2’-Dimethylbenzoin (CAS 4389-39-3)
- 5-(Bromomethyl)-2-methylbenzoic acid (CAS 72985-19-4)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
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