6-Bromo-2,3-dimethylimidazo[1,2-a]pyridin-8-amine CAS 212268-15-0
| CAS No. | 212268-15-0 |
| Molecular Formula | C9H10BrN3 |
| Molecular Weight | 240.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Bromo-2,3-dimethylimidazo[1,2-a]pyridin-8-amine (CAS 212268-15-0), molecular formula C9H10BrN3 and molecular weight 240.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Bromo-2,3-dimethylimidazo[1,2-a]pyridin-8-amine (C9H10BrN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 6-Bromo-2,3-dimethylimidazo[1,2-a]pyridin-8-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10BrN3 |
| Molecular Weight | 240.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
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Recommended Standards
- 6-Bromo-1-methyl-2,3-dihydroquinolin-4(1H)-one (CAS 99057-84-8)
- 6-Bromo-2-isopropyl-3H-imidazo[4,5-b]pyridine (CAS 68175-14-4)
- 6-Bromo-1-ethyl-1H-benzimidazol-2-amine (CAS 24810-29-5)
- 6-Bromo-2-methyl-3,4-dihydroisoquinolin-1(2H)-one (CAS 724422-42-8)
- 2-(3,3,5-Trimethylcyclohexyl)propanoic acid (CAS 1558770-80-1)
- 4-Chloro-3-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 1638764-15-4)
- N-(4-((5-(2,2-Dicyanovinyl)furan-2-yl)sulfonyl)phenyl)acetamide (CAS 64251-81-6)
- Ethyl 9-(2-ethoxy-2-oxoethyl)-7-hydroxy-9-azabicyclo[3.3.1]nonane-3-carboxylate (CAS 115956-04-2)
- (S)-tert-Butyl 4-((R)-2-(((tert-butyldimethylsilyl)oxy)methyl)-5-hydroxypentyl)-2,2-dimethyloxazolidine-3-carboxylate (CAS 942144-35-6)
- H-Ile-NHOH (CAS 31982-77-1)
- (R)-(2-Amino-3,3-dimethyl-butyl)-carbamic acid tert-butyl ester (CAS 1218943-99-7)
- 1,4-Dioxa-8-aza-spiro[4.5]decan-7-one (CAS 6813-54-3)
- 2-phenoxyethyl chloroformate (CAS 34743-87-8)
- Semaglutide impurity 261 (CAS CATO-C4X-2226261)
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