n-(1h-1,2,4-Triazol-5-yl)picolinamide CAS 21233-29-4

Purity 97%+In StockPharmaceutical Standards
CAS No.21233-29-4
Molecular FormulaC8H7N5O
Molecular Weight189.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

n-(1h-1,2,4-Triazol-5-yl)picolinamide CAS 21233-29-4 chemical structure

Description

CATO supplies n-(1h-1,2,4-Triazol-5-yl)picolinamide (CAS 21233-29-4), a certified reference material (molecular formula C8H7N5O, MW 189.17 g/mol) for analytical method development and quality control.

The molecular framework of n-(1h-1,2,4-Triazol-5-yl)picolinamide (C8H7N5O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H7N5O
Molecular Weight189.17 g/mol
AppearancePale yellow to yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963
Nitrogen Atoms5

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