4-Chloro-1-cyclopentyl-1h-pyrazolo[3,4-d]pyrimidine CAS 21253-99-6
| CAS No. | 21253-99-6 |
| Molecular Formula | C10H11ClN4 |
| Molecular Weight | 222.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Chloro-1-cyclopentyl-1h-pyrazolo[3,4-d]pyrimidine (C10H11ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-Chloro-1-cyclopentyl-1h-pyrazolo[3,4-d]pyrimidine (CAS 21253-99-6), a certified reference material (molecular formula C10H11ClN4, MW 222.67 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-1-cyclopentyl-1h-pyrazolo[3,4-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClN4 |
| Molecular Weight | 222.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 4-Chloro-n-(4-cyanophenyl)butanamide (CAS 1016674-12-6)
- 6-Chloro-3-cyclopentyl-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094260-24-8)
- 2-Chloro-6-(2-isopropyl-1H-imidazol-1-yl)pyrazine (CAS 1094842-75-7)
- 5-Chloro-6-cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1135283-21-4)
- (5-Chloro-3-methyl-1-phenyl-1h-pyrazol-4-yl)methanol (CAS 1136-60-3)
- 4-Chloro-7-methoxy-2-methylquinolin-8-amine (CAS 113698-10-5)
- 1-(2-Chloro-6-methylphenyl)-3-methyl-1H-pyrazol-5(4H)-one (CAS 117-23-7)
- 4-Chloro-5-ethyl-2-(furan-2-yl)-6-methylpyrimidine (CAS 1178851-16-5)
Recommended Standards
- 4-(Chloromethyl)-7-ethyl-2H-1-benzopyran-2-one (CAS 554423-21-1)
- 4-Chloro-2-(3,5-dimethyl-1h-pyrazol-1-yl)-6-methylpyrimidine (CAS 65004-43-5)
- 4-(Chloromethyl)-7,8-dimethyl-2H-chromen-2-one (CAS 41295-57-2)
- 4-Chlorospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 2089314-95-2)
- (E)-2-((4-ethyl-5-styryl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 478065-59-7)
- Methyl 3-hydroxypentanoate (CAS 56009-31-5)
- 5-Nitro-3-propoxybenzofuran-2-carboxylic acid (CAS 1707581-39-2)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinaldehyde (CAS 1310404-20-6)
- [amino(4-fluorophenyl)methylidene]amino prop-2-enoate (CAS 19580-38-2)
- N1,N1-dimethylnaphthalene-1,4-diamine hydrochloride (CAS 7475-05-0)
- 2-((4-Methoxybenzyl)sulfonyl)-4,6-dimethyl-3-tosylpyridine (CAS 478245-41-9)
- 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperidine hydrochloride (CAS 1021186-08-2)
- 1-(5-Chloro-2-hydroxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 870614-04-3)
- Semaglutide Impurity 145 (CAS CATO-C4X-2226145)
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