(R,E)-4-((tert-Butyldimethylsilyl)oxy)pent-2-enoic acid CAS 2126144-78-1

Purity 97%+In StockPharmaceutical Standards
CAS No.2126144-78-1
Molecular FormulaC11H22O3Si
Molecular Weight230.38 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(R,E)-4-((tert-Butyldimethylsilyl)oxy)pent-2-enoic acid CAS 2126144-78-1 chemical structure

Description

The molecular framework of (R,E)-4-((tert-Butyldimethylsilyl)oxy)pent-2-enoic acid (C11H22O3Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO supplies (R,E)-4-((tert-Butyldimethylsilyl)oxy)pent-2-enoic acid (CAS 2126144-78-1), a certified reference material (molecular formula C11H22O3Si, MW 230.38 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H22O3Si
Molecular Weight230.38 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1997

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