1-(Azetidin-3-yl)-4-(3-methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one hydrochloride CAS 2126161-76-8
| CAS No. | 2126161-76-8 |
| Molecular Formula | C10H14N4O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(Azetidin-3-yl)-4-(3-methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one hydrochloride (CAS 2126161-76-8), molecular formula C10H14N4O2HCl and molecular weight 258.71 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(Azetidin-3-yl)-4-(3-methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one hydrochloride (C10H14N4O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14N4O2 HCl |
| Molecular Weight | 258.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Azetidin Standards
- 4-(Azetidin-1-yl)cyclohexan-1-amine dihydrochloride (CAS 1001347-27-8)
- 4-(Azetidin-1-ylmethyl)-1H-indole (CAS 1001395-40-9)
- 2-(Azetidin-1-yl)acetic acid (CAS 1008304-81-1)
- Azetidin-3-yl methylcarbamate hydrochloride (CAS 1009368-29-9)
- 5-(Azetidin-3-yl)-2-methyl-tetrazole (CAS 1009409-58-8)
- 2-((Azetidin-3-yloxy)methyl)-5-methyl-1,3,4-oxadiazole (CAS 1009409-61-3)
- Azetidin-3-yl methylcarbamate (CAS 1009409-62-4)
- 1-(Azetidin-3-ylmethyl)piperidine (CAS 1012784-24-5)
Recommended Standards
- 2-Chloro-5-fluorobenzeneboronic acid pinacol ester, 97% (CAS 870486-41-2)
- 3-(3-(Bromomethyl)phenyl)-5-methyl-1,2,4-oxadiazole (CAS 253273-90-4)
- 4-Methoxy-3-((4-nitro-1H-pyrazol-1-yl)methyl)benzaldehyde oxime (CAS 512810-23-0)
- N-Methyl-1-(1,3,5-trimethyl-1H-pyrazol-4-yl)methanamine hydrochloride (CAS 1188264-82-5)
- Fenamiphos-Sulfoxide (CAS 31972-43-7)
- (R)-3-Isopropylpiperazine-2,5-dione (CAS 143673-66-9)
- 3,5-Dimethyl-1-(pentan-3-yl)-1h-pyrazol-4-amine (CAS 1248935-11-6)
- 6-Bromo-7-methylpyrazolo[1,5-a]pyridine (CAS 1427382-24-8)
- Tert-butyl 5-amino-3-methyl-3,6-dihydropyridine-1(2H)-carboxylate (CAS 2306265-67-6)
- Calcineurin Autoinhibitory Peptide (CAS 148067-21-4)
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