5-((4-Methylpiperazin-1-yl)methyl)thiophene-2-carboxylic acid dihydrochloride CAS 2126178-22-9
| CAS No. | 2126178-22-9 |
| Molecular Formula | C11H16N2O2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-((4-Methylpiperazin-1-yl)methyl)thiophene-2-carboxylic acid dihydrochloride (CAS 2126178-22-9) is a high-purity analytical reference standard with the molecular formula C11H16N2O2SHCl and a molecular weight of 276.78 g/mol.
5-((4-Methylpiperazin-1-yl)methyl)thiophene-2-carboxylic acid dihydrochloride (C11H16N2O2SHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-((4-Methylpiperazin-1-yl)methyl)thiophene-2-carboxylic acid dihydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O2S 2*HCl |
| Molecular Weight | 276.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylpiperazin Standards
- 3-(1-Methylpiperazin-4-yl)-4-methylsulfonylaniline (CAS 1000018-41-6)
- 1-(4-Methylpiperazin-1-yl)pentan-1-one (CAS 10001-06-6)
- 1000577-07-0 5-ethyl-1-methylpiperazin-2-one (CAS 1000577-07-0)
- 1-ethyl-5-methylpiperazin-2-one (CAS 1000577-11-6)
- 4-[(4-methylpiperazin-1-yl)carbonyl]benzonitrile (CAS 1000932-49-9)
- 4-[2-(4-methylpiperazin-1-yl)ethoxy]phenol (CAS 100221-01-0)
- (5-(4-Methylpiperazin-1-yl)-2-nitrophenyl)methanol (CAS 1002556-21-9)
- (4-(3-(4-Methylpiperazin-1-yl)propoxy)phenyl)boronic acid (CAS 1003028-43-0)
Recommended Standards
- 2-Chloro-4-(4-methylphenyl)pyridine (CAS 1202574-24-0)
- N-(2-(N-Benzylsulfamoyl)ethyl)-3-methoxybenzamide (CAS 899967-19-2)
- (R)-3-(1-Aminoethyl)oxetan-3-ol (CAS 2200475-27-8)
- 5-Bromo-2-(pyrrolindin-1-ylcarbonyl)pyridine (CAS 742085-70-7)
- Methyl 5-((2-ethoxyphenyl)carbamoyl)-2-(2-fluorobenzamido)-4-methylthiophene-3-carboxylate (CAS 335410-33-8)
- 1-(Chloromethyl)piperidin-2-one (CAS 68116-79-0)
- 1,1'-(Ethyne-1,2-diylbis(4,1-phenylene))bis(ethan-1-one) (CAS 29619-42-9)
- (4-(Difluoromethyl)-3-methylpyridin-2-yl)methanol (CAS 1804714-45-1)
- N-(4-(((5-Nitrofuran-2-yl)methyl)thio)phenyl)acetamide (CAS 61266-73-7)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com