5-((Methylamino)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one CAS 21263-85-4
| CAS No. | 21263-85-4 |
| Molecular Formula | C6H9N3OS |
| Molecular Weight | 171.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-((Methylamino)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one.
5-((Methylamino)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 21263-85-4), molecular formula C6H9N3OS and molecular weight 171.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-((Methylamino)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (C6H9N3OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9N3OS |
| Molecular Weight | 171.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methylamino Standards
- 6-(Methylamino)-2-(methylthio)pyrimidin-4(3H)-one (CAS 120270-05-5)
- 1-[5-(Methylamino)-1,2,4-thiadiazol-3-yl]-2-propanone (CAS 257862-97-8)
- 5-(Methylamino)-2-(methylthio)-1H-imidazole-4-carbaldehyde (CAS 339364-05-5)
- Methyl 5-(methylamino)thiophene-2-carboxylate (CAS 859855-63-3)
- 2-(methylamino)-6,7-dihydro-3H-purin-6-one (CAS 10030-78-1)
- 2-(1-(Methylamino)cyclohexyl)acetic acid (CAS 1199776-35-6)
- Methyl 4-(methylamino)cyclohexane-1-carboxylate (CAS 1378727-69-5)
- 2-(Methylamino)-1-(4-methylpiperazin-1-yl)ethan-1-one (CAS 166187-00-4)
Recommended Standards
- 5-((Allylthio)methyl)isoxazol-3(2H)-one (CAS 89660-70-8)
- 5-(2-Aminoethyl)thiophene-2-carboxylic acid (CAS 897095-14-6)
- 4-Propylthiazole-5-carboxylic acid (CAS 81569-65-5)
- 5-(Dimethylamino)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 53250-06-9)
- 4-Methyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzamide (CAS 2246890-53-7)
- 4-Chloro-N,2-dimethoxy-N-methylbenzamide (CAS 205320-02-1)
- n-Benzyl-10h-phenothiazine-10-carboxamide (CAS 4297-08-9)
- Pyridoxine Impurity 75 (CAS CATO-C4X-187775)
- 4,6-Dimethylpyrimidine-2-sulfonyl fluoride (CAS 35762-73-3)
- Methyl 1-((tert-butoxycarbonyl)amino)cyclobutanecarboxylate (CAS 880166-10-9)
- 1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl butanoate (CAS 1538551-54-0)
- Ethyl 2-(2-bromo-4,5-dimethoxyphenyl)-2-oxoacetate (CAS 1275526-40-3)
- (S)-4-Amino-5-fluoro-2-((1,1,1-trifluoropropan-2-yl)oxy)benzoic acid (CAS 2757405-72-2)
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