4-((Dimethylamino)methylene)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one CAS 21272-28-6

Purity 97%+In StockPharmaceutical Standards
CAS No.21272-28-6
Molecular FormulaC12H13N3O
Molecular Weight215.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-((Dimethylamino)methylene)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one CAS 21272-28-6 chemical structure

Description

4-((Dimethylamino)methylene)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one (CAS 21272-28-6) is a high-purity analytical reference standard with the molecular formula C12H13N3O and a molecular weight of 215.25 g/mol.

Structurally, 4-((Dimethylamino)methylene)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one (C12H13N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 215.25 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-((Dimethylamino)methylene)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H13N3O
Molecular Weight215.25 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963
Nitrogen Atoms3

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