n-(4-Chlorophenyl)-n-(4-formyl-1,3-thiazol-2-yl)acetamide CAS 21278-72-8

Purity 97%+In StockPharmaceutical Standards
CAS No.21278-72-8
Molecular FormulaC12H9ClN2O2S
Molecular Weight280.73 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

n-(4-Chlorophenyl)-n-(4-formyl-1,3-thiazol-2-yl)acetamide CAS 21278-72-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 280.73 g/mol gives n-(4-Chlorophenyl)-n-(4-formyl-1,3-thiazol-2-yl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

n-(4-Chlorophenyl)-n-(4-formyl-1,3-thiazol-2-yl)acetamide (CAS 21278-72-8), molecular formula C12H9ClN2O2S and molecular weight 280.73 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C12H9ClN2O2S, n-(4-Chlorophenyl)-n-(4-formyl-1,3-thiazol-2-yl)acetamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 280.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), n-(4-Chlorophenyl)-n-(4-formyl-1,3-thiazol-2-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H9ClN2O2S
Molecular Weight280.73 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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