2-(4-Chloronaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 2128285-49-2
| CAS No. | 2128285-49-2 |
| Molecular Formula | C16H18BClO2 |
| Molecular Weight | 288.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-Chloronaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(4-Chloronaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2128285-49-2), a certified reference material (molecular formula C16H18BClO2, MW 288.58 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4-Chloronaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C16H18BClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18BClO2 |
| Molecular Weight | 288.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
Related Chloronaphthalen Standards
- 2-(1-Chloronaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1154740-95-0)
- 2-(2-Chloronaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2621937-36-6)
- 2-(6-Chloronaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 870822-85-8)
- 2-((4-Chloronaphthalen-1-yl)oxy)-4-methylaniline (CAS 946729-16-4)
- 2-(5-Chloronaphthalen-1-yl)benzo[d]oxazol-5-amine (CAS 443289-56-3)
- 1-((8-Chloronaphthalen-1-yl)sulfonyl)pyrrolidine (CAS 446054-17-7)
- 1-Chloronaphthalen-2-yl diethylcarbamate (CAS 526190-31-8)
- 4-((4-Chloronaphthalen-1-yl)oxy)aniline (CAS 76590-21-1)
Recommended Standards
- 5-Chloro-2,6-bis(trifluoromethyl)-1H-1,3-benzodiazole (CAS 171809-86-2)
- 2-(2-Bromophenyl)-4-(chloromethyl)thiazole (CAS 953907-60-3)
- 7-Chloro-2,5-bis(trifluoromethyl)-1H-benzo[d]imidazole (CAS 1209789-75-2)
- 2-(3-bromophenyl)-4-(chloromethyl)-1,3-thiazole (CAS 900640-85-9)
- 1-Chloro-4-((trifluoromethyl)sulfinyl)benzene (CAS 708-66-7)
- Pyrimido[5,4-e][1,2,4]triazin-5-amine (CAS 19359-15-0)
- 2-[(E)-[(2-Chlorophenyl)methylidene]amino]-5-phenylfuran-3-carbonitrile (CAS 478033-40-8)
- N-(2-(6,7-Dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)acetamide (CAS 851402-90-9)
- 4-(tert-Butyl)-3-iodophenol (CAS 1243411-01-9)
- Maesaquinone (CAS 19833-20-6)
- 2-(6-(tert-Butoxycarbonyl)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl)acetic acid (CAS 1206821-44-4)
- Boc-Asp(OBzl)-Phe-OH (CAS 68763-45-1)
- 3-(2-Bromopyridin-6-yl)thiazolidine (CAS 1774894-76-6)
- Semaglutide Impurity 12 (CAS CATO-C4X-222612)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com