4-Amino-2-methylbenzene-1-sulfonyl fluoride CAS 21320-92-3
| CAS No. | 21320-92-3 |
| Molecular Formula | C18H19FI2N2 |
| Molecular Weight | 536.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Amino-2-methylbenzene-1-sulfonyl fluoride (CAS 21320-92-3) is a high-purity analytical reference standard with the molecular formula C18H19FI2N2 and a molecular weight of 536.16 g/mol.
The molecular framework of 4-Amino-2-methylbenzene-1-sulfonyl fluoride (C18H19FI2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Amino-2-methylbenzene-1-sulfonyl fluoride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H19FI2N2 |
| Molecular Weight | 536.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 3-Amino-N-(2-chlorobenzyl)-6-(3,4-dimethoxybenzyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 939889-17-5)
- 5-Amino-6-chloro-2-phenylpyridazin-3(2H)-one (CAS 1698-59-5)
- 1-(29-Amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosyl)-1H-pyrrole-2,5-dione (CAS 2170654-78-9)
- (R)-5-Amino-2-(((benzyloxy)carbonyl)(diphenyl(p-tolyl)methyl)amino)-5-oxopentanoic acid (CAS 200716-85-4)
- Ethyl 2-(1-(2-amino-2-oxoethyl)-2-oxoindolin-3-ylidene)-5-(2-chlorophenyl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 324566-10-1)
- Ethyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-[({3-cyano-5H,6H,7H,8H,9H,10H-cycloocta[b]pyridin-2-yl}sulfanyl)methyl]-4H-pyran-3-carboxylate (CAS 316358-94-8)
- Ethyl 6-amino-4-(4-chlorophenyl)-5-cyano-2-(((3-cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)thio)methyl)-4H-pyran-3-carboxylate (CAS 339163-49-4)
- 1-(4-(4-Amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea (CAS 501693-25-0)
Recommended Standards
- 4-Chloro Maraviroc-d6 (CAS 1346597-32-7)
- 3,3-Bis(3-bromo-4-hydroxy-5-methoxyphenyl)isobenzofuran-1(3H)-one (CAS 6335-86-0)
- Loratadine Impurity 64 (CAS CATO-C4X-142664)
- Kinesore (CAS 363571-83-9)
- N-(cyclobutylmethyl)-3-fluoro-4-methylaniline (CAS 1478874-07-5)
- Ammonium Iodate (CAS 13446-09-8)
- Methyl 3-amino-3-(tetrahydro-2h-pyran-4-yl)propanoate (CAS 1249491-73-3)
- 5-Fluoro-1-methyl-3-(piperidin-4-yl)-1H-indazole hydrochloride (CAS 1980054-46-3)
- Amphotericin B Impurity 12 (CAS CATO-C4X-184412)
- 4-(Trans-4-propylcyclohexyl)benzonitrile (CAS 61203-99-4)
- 5-(4-Methoxypiperidin-1-yl)furan-2-carbaldehyde (CAS 1250212-35-1)
- Methyl 3-(4-(chloromethyl)phenoxy)-4-methoxybenzoate (CAS 308804-89-9)
- 6-(3-hydroxyprop-1-ynyl)-2H-chromene-3-carboxylic acid (CAS 2557694-04-7)
- Rac1 Inhibitor F56, control peptide (CAS 1315378-77-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com