Methyl 3-iodo-4-methyl-5-nitrobenzoate CAS 21323-99-9
| CAS No. | 21323-99-9 |
| Molecular Formula | C9H8INO4 |
| Molecular Weight | 321.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 3-iodo-4-methyl-5-nitrobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 3-iodo-4-methyl-5-nitrobenzoate (CAS 21323-99-9), molecular formula C9H8INO4 and molecular weight 321.07 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 3-iodo-4-methyl-5-nitrobenzoate (C9H8INO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H8INO4 |
| Molecular Weight | 321.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl 3-iodo-2-methyl-5-nitrobenzoate (CAS 1005499-48-8)
- Ethyl 5-iodo-2-nitrobenzoate (CAS 1260830-52-1)
- Methyl 2-(4-iodo-3-nitrophenyl)acetate (CAS 1261678-36-7)
- Methyl 5-iodo-2-methyl-3-nitrobenzoate (CAS 1511381-00-2)
- 2-Iodo-6-methoxy-4-(2-nitrovinyl)phenol (CAS 662160-77-2)
- Ethyl 2-iodo-5-nitrobenzoate (CAS 835916-53-5)
- Ethyl 4-iodo-3-nitrobenzoate (CAS 57362-77-3)
- Methyl 2-iodo-3-methyl-5-nitrobenzoate (CAS 908597-08-0)
Recommended Standards
- Methyl 2-iodo-5-methyl-3-nitrobenzoate (CAS 854645-22-0)
- 850864-49-2 Benzoic acid, 3-iodo-5-nitro-, ethyl ester (CAS 850864-49-2)
- (4-((Tert-butyldimethylsilyl)oxy)-3,5-dichlorophenyl)boronic acid (CAS 1150114-46-7)
- tributyl(methoxy)stannane (CAS 1067-52-3)
- 2-(2-(4-Carboxypiperidin-1-yl)-2-oxoethyl)isothiouronium chloride (CAS 1046445-52-6)
- N2-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine (CAS 101988-70-9)
- 2-(5-Methylpyridin-2-yl)-6-phenyl-1,3,6,2-dioxazaborocane (CAS 872054-54-1)
- 8-Chloro-3-iodo-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 2383187-31-1)
- 1-Chloroacridin-9(10H)-one (CAS 91311-45-4)
- Capecitabine Impurity 9 (CAS 1262133-64-1)
- 4-Allyl-5-fluoro-1H-pyrrolo[2,3-b]pyridine (CAS 1228665-89-1)
- Phillygenin (CAS 487-39-8)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-methoxy-4-methylphenyl)propanoic acid (CAS 1379865-86-7)
- Fibrinopeptide A (human) (CAS 25422-31-5)
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