5-Chloro-4-fluoro-2-nitrobenzaldehyde CAS 213382-47-9
| CAS No. | 213382-47-9 |
| Molecular Formula | C7H3ClFNO3 |
| Molecular Weight | 203.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-4-fluoro-2-nitrobenzaldehyde is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-4-fluoro-2-nitrobenzaldehyde (CAS 213382-47-9), a certified reference material (molecular formula C7H3ClFNO3, MW 203.56 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-4-fluoro-2-nitrobenzaldehyde (C7H3ClFNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-4-fluoro-2-nitrobenzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3ClFNO3 |
| Molecular Weight | 203.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-fluoro-5-nitrobenzaldehyde (CAS 1639298-89-7)
- 4-Chloro-5-fluoro-2-nitrobenzaldehyde (CAS 184843-93-4)
- 2-Chloro-4-fluoro-5-nitrobenzaldehyde (CAS 99329-85-8)
- 2-Chloro-6-fluoro-3-nitrobenzaldehyde (CAS 899821-26-2)
- 3-Chloro-4-(difluoromethoxy)benzonitrile (CAS 1247836-44-7)
- 2-Chloro-4-(difluoromethoxy)benzonitrile (CAS 1260813-98-6)
- 2-Chloro-6-(difluoromethoxy)benzonitrile (CAS 1261618-35-2)
- 2-Chloro-3-(difluoromethoxy)benzonitrile (CAS 1261676-33-8)
Recommended Standards
- 4-Fluoro-2-nitrobenzoyl chloride (CAS 57750-82-0)
- 5-Fluoro-2-nitrobenzoyl chloride, 98% (CAS 394-02-5)
- 3-Nitro-4-fluorobenzoyl chloride (CAS 400-94-2)
- 2-Fluoro-6-nitrobenzoyl chloride (CAS 50424-88-9)
- Methyl 2-ethylpiperidine-4-carboxylate (CAS 1552163-93-5)
- 1-[2-Amino-4-chloro-5-(methylsulfanyl)phenyl]ethan-1-one (CAS 98440-96-1)
- Diethyl 3-amino-1,5-pentaneÂdioic acid (CAS 51865-85-1)
- CAS 2707415-29-8 (CAS 2707415-29-8)
- 1-Benzhydryl-3-iodoazetidine (CAS 125735-40-2)
- 2-Methyl-3,4-dihydroquinoline-1(2H)-carbaldehyde (CAS 27850-49-3)
- 1-(2-Phenylquinolin-4-yl)ethan-1-one (CAS 7505-73-9)
- Cyclohexyl (5-amino-3-phenyl-1,2-dihydropyrido[3,4-b]pyrazin-7-yl)carbamate (CAS 87607-30-5)
- 2-Amino-5-chloro-4-methylphenol (CAS 1267409-17-5)
- Semaglutide Impurity 1(OtBu-Ste-D-γGlu(OtBu)-AEEA-AEEA-OH) (CAS CATO-C4X-22261)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com