thieno[2,3-b]pyridin-5-ol CAS 21344-26-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including thieno[2,3-b]pyridin-5-ol.

thieno[2,3-b]pyridin-5-ol (CAS 21344-26-3) is a high-purity analytical reference standard with the molecular formula C7H13NOS and a molecular weight of 159.25 g/mol.

Based on its molecular formula C7H13NOS, thieno[2,3-b]pyridin-5-ol contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 159.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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