4-(5-Bromo-1H-indol-3-yl)pyrimidin-2-amine CAS 213473-00-8
| CAS No. | 213473-00-8 |
| Molecular Formula | C12H9BrN4 |
| Molecular Weight | 289.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 289.13 g/mol gives 4-(5-Bromo-1H-indol-3-yl)pyrimidin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(5-Bromo-1H-indol-3-yl)pyrimidin-2-amine (CAS 213473-00-8), molecular formula C12H9BrN4 and molecular weight 289.13 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution, 4-(5-Bromo-1H-indol-3-yl)pyrimidin-2-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 289.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9BrN4 |
| Molecular Weight | 289.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
- 4-(4-Amino-2-bromophenoxy)benzonitrile (CAS 66658-88-6)
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- 3-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[e][1,3]oxazin-2-one (CAS 2020021-57-0)
- 4-(Benzyloxy)-2-bromonicotinonitrile (CAS 727737-51-1)
- 1-Cyclopentyl-3-(4,6-dimethylpyrimidin-2-yl)guanidine (CAS 376615-19-9)
- 4'-Bromo-3-chloro-2-methyl-1,1'-biphenyl (CAS 1443352-49-5)
- 6-(2-Chlorophenyl)-4-imino-3-phenyl-1H,2H,3H,4H,7H,8H-[1,3]diazino[5,4-d]pyrimidine-2,8-dione (CAS 866019-01-4)
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