Baloxavir Impurity C18 CAS 2136287-59-5
| CAS No. | 2136287-59-5 |
| Molecular Formula | C19H22N2O6 |
| Molecular Weight | 374.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Baloxavir Impurity C18 (C19H22N2O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Baloxavir Impurity C18 (CAS 2136287-59-5) is a certified pharmaceutical impurity reference standard with the molecular formula C19H22N2O6 and a molecular weight of 374.39 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Baloxavir Impurity C18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H22N2O6 |
| Molecular Weight | 374.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Baloxavir Standards
- Baloxavir Marboxil Impurity 185 (CAS CATO-C4X-2108185)
- Baloxavir impurity C868 (CAS 1985607-65-5)
- Baloxavir Impurity 2 (CAS CATO-C4X-21082)
- Baloxavir Impurity 4 (CAS CATO-C4X-21084)
- Baloxavir Marboxil Impurity 211 (CAS CATO-C4X-2108211)
- Baloxavir Marboxil Impurity 154 (CAS CATO-C4X-2108154)
- Baloxavir Marboxil Impurity 212 (CAS CATO-C4X-2108212)
- Baloxavir Impurity 108 (CAS 2640188-50-5)
Recommended Standards
- Methyl 1-benzyl-2-imino-10-methyl-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate (CAS 371926-99-7)
- N-(2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-5-yl)benzamide (CAS 50699-22-4)
- Ethyl 5-formyl-2-((5-formyl-4-methyl-3-(propionyloxy)-1H-pyrrol-2-yl)methyl)-4-methyl-1H-pyrrole-3-carboxylate (CAS 6339-67-9)
- N-(2-(2-Methoxy-6H-dipyrido[2,3-a:3',2'-e]pyrrolizin-11-yl)ethyl)furan-2-carboxamide (CAS 874484-20-5)
- Guaiazulene Impurity 1 (CAS CATO-C4X-22371)
- Relebactam Impurity 64 (CAS CATO-C4X-214464)
- Ciclosporin EP Impurity F (CAS 437611-17-1)
- 2-Bromo-5-chloro-3-nitrobenzene-1-sulfonyl chloride (CAS 1340462-42-1)
- n-(2-Hydroxyethyl)-2-methyl-5-nitrobenzenesulfonamide (CAS 68003-40-7)
- Venetoclax Impurity 49 (CAS CATO-C4X-249549)
- [1-(aminomethyl)-4-methylcyclohexyl]methanamine (CAS 1507983-56-3)
- 3-amino-6,8-dichloro-1,2,4,9-tetrahydrocarbazole-3-carboxylic acid (CAS 874112-29-5)
- 4-(1-(4-Nitrophenyl)-1H-1,2,3-triazol-5-yl)aniline (CAS 62546-65-0)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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